Clinical trial Recruiting at 1 site Interventional

Single chest drain versus two drains after esophagectomy

Official title: Outcomes of Transhiatal Drain Placement in Esophagectomy, a Randomised Control Trial

Run by Khyber Teaching Hospital · NCT07125248 · Data updated 2026-11-12

This will test whether using one chest drain instead of two helps people recover more easily after open surgery to remove esophageal cancer.

Quick facts

Study typeInterventional
SexAll
Enrollment68 (estimated)
SponsorKhyber Teaching Hospital
Academic / other
Locations1 site (Peshawar, Khyberpukhtunkhwa)
StatusRecruiting
StartedFebruary 28, 2025
Main results expectedSeptember 1, 2025
Study endsSeptember 10, 2025
Registry record updatedAugust 15, 2025
Trial IDNCT07125248 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults scheduled for open esophagectomy for esophageal carcinoma at Khyber Teaching Hospital who consent to participate are the intended candidates.

Probably not a fit

Patients having minimally invasive esophagectomy, those operated for benign disease, or patients with conditions requiring multiple drains may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares outcomes for patients undergoing open esophagectomy who receive either a single pleural drain or the conventional two chest drains. Participants treated at the Khyber Teaching Hospital will receive one of the two drainage approaches during surgery and be followed for postoperative outcomes. Key outcomes include pain, mobility, pleural fluid accumulation, need for additional drainage, and other complications. The trial includes all consenting adults having open esophagectomy for carcinoma and excludes those operated for benign disease.

Why it matters

Potential benefit: If successful, using a single drain could reduce pain and improve early mobility while maintaining safe control of chest fluid.

How similar studies have gone: Recent reports suggest a single chest drain can be safe and effective after thoracic surgery, so this trial builds on emerging evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients undergoing open esophagectomy for carcinoma of esophagus

Exclusion Criteria:

* Non consenting individuals esophagectomy for benign disease

Where it's running

  • Khyber teaching hospital
    Peshawar, Khyberpukhtunkhwa, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.