Single chest drain versus two drains after esophagectomy
Official title: Outcomes of Transhiatal Drain Placement in Esophagectomy, a Randomised Control Trial
Run by Khyber Teaching Hospital · NCT07125248 · Data updated 2026-11-12
This will test whether using one chest drain instead of two helps people recover more easily after open surgery to remove esophageal cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 68 (estimated) |
| Sponsor | Khyber Teaching Hospital Academic / other |
| Locations | 1 site (Peshawar, Khyberpukhtunkhwa) |
| Status | Recruiting |
| Started | February 28, 2025 |
| Main results expected | September 1, 2025 |
| Study ends | September 10, 2025 |
| Registry record updated | August 15, 2025 |
| Trial ID | NCT07125248 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults scheduled for open esophagectomy for esophageal carcinoma at Khyber Teaching Hospital who consent to participate are the intended candidates.
✕Probably not a fit
Patients having minimally invasive esophagectomy, those operated for benign disease, or patients with conditions requiring multiple drains may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares outcomes for patients undergoing open esophagectomy who receive either a single pleural drain or the conventional two chest drains. Participants treated at the Khyber Teaching Hospital will receive one of the two drainage approaches during surgery and be followed for postoperative outcomes. Key outcomes include pain, mobility, pleural fluid accumulation, need for additional drainage, and other complications. The trial includes all consenting adults having open esophagectomy for carcinoma and excludes those operated for benign disease.
Why it matters
Potential benefit: If successful, using a single drain could reduce pain and improve early mobility while maintaining safe control of chest fluid.
How similar studies have gone: Recent reports suggest a single chest drain can be safe and effective after thoracic surgery, so this trial builds on emerging evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients undergoing open esophagectomy for carcinoma of esophagus Exclusion Criteria: * Non consenting individuals esophagectomy for benign disease
Where it's running
-
Khyber teaching hospital
Peshawar, Khyberpukhtunkhwa, Pakistan Recruiting
Study contacts
- Study coordinator: Saeed Sarwar, MBBS
- Email: saeedkmc2020@gmail.com
- Phone: +923420973863
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.