Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 18 to 70

Perioperative bupivacaine at knee arthroscopy port sites to reduce pain and improve movement

Official title: Effectiveness of Per-Operative Bupivicaine in Reducing Postoperative Pain at Port Site and Improving Mobility in Knee Arthoscopic Procedures

Run by Khyber Teaching Hospital · NCT07090928 · Data updated 2026-11-12

This trial tests whether applying bupivacaine around knee arthroscopy port sites during surgery reduces postoperative port-site pain and helps patients move sooner.

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Quick facts

PhasePhase 4
Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment60 (estimated)
SponsorKhyber Teaching Hospital
Academic / other
Locations1 site (Peshawar, KPK)
StatusRecruiting
StartedMarch 10, 2026
Main results expectedJune 2026
Study endsJune 2026
Registry record updatedJune 25, 2026
Trial IDNCT07090928 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18-70 undergoing elective knee arthroscopy who can understand the pain scale.

Probably not a fit

Patients who have hypersensitivity to bupivacaine, chronic opioid use, or conditions affecting mobility may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines the effect of infiltrating 0.5% bupivacaine at each arthroscopy port site during knee procedures versus placebo. Adults undergoing elective knee arthroscopy are randomized to receive either the local anesthetic around port incisions or a placebo, with pain and early mobility as key outcomes. The goal is to determine if targeted port-site analgesia can lower pain scores and facilitate earlier functional recovery. The investigation aims to add evidence on optimizing postoperative pain control in minimally invasive knee surgery.

Why it matters

Potential benefit: If successful, patients could experience less port-site pain and improved early mobilization after knee arthroscopy.

How similar studies have gone: Prior work supports local infiltration for postoperative pain in various surgeries, but specific benefit for port-site pain in knee arthroscopy is not conclusively established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria Either Male or Female Age range: 18-70 Years Patients scheduled to undergo elective knee arthroscopic procedures Able to understand the VAS pain scale Exclusion Criteria Either Male or Female Age range: 18-70 Years Patients scheduled to undergo elective knee arthroscopic procedures Able to understand the VAS pain scale Known hypersensitivity or allergy to bupivacaine or any local anesthetics Chronic pain conditions requiring regular pain medications History of drug abuse (mainly to opioids) Pregnant women Pre-existing impaired knee mobility No willing to participate in trial

Where it's running

  • Khyber teaching Hospital Peshawer
    Peshawar, Kpk, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.