Collection of gut microbiota samples from patients with bone or joint infections on antibiotic therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect biological samples from the gut microbiota of patients suffering from bone or joint infections who are being treated with subcutaneous prolonged suppressive antibiotic therapy using betalactamine. The focus is on understanding the impact of this treatment on gut microbiota and the potential development of antibiotic resistance. The study is particularly relevant for patients who cannot undergo optimal surgical interventions due to age or other factors. By analyzing these samples, researchers hope to gain insights into the effectiveness and safety of this treatment approach.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients having a bone or joint infection
* Patients treated by a suppressive subcutaneous antibiotherapy with betalactamine

Exclusion Criteria:

* None

Where it's running

• Centre de référence des infections ostéo-articulaires de Lyon - Hôpital de la Croix-Rousse
  Lyon, France Recruiting

Study contacts

• Study coordinator: Tristan FERRY, MD, PhD
• Email: tristan.ferry@chu-lyon.fr
• Phone: 04 72 07 11 07

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Oral antibiotics for treating bone and joint infections in children

  This study is testing if giving oral antibiotics first can effectively and safely treat uncomplicated bone and joint infections in children and teens aged 3 months to 17 years.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen Ø · NCT06827496

• Comparing two types of spacers for treating knee joint infections

  This study is testing which type of spacer works better for treating knee joint infections in patients who have had knee replacement surgery.

  Recruiting Northwestern University · Chicago, Illinois · NCT06293352

• Observational study on phage therapy requests for bone infections

  This study looks at how many patients are asking for phage therapy to treat bone infections over a period of time.

  Recruiting Hospices Civils de Lyon · Lyon · NCT05883995

• Comparing infection rates after hip replacement using a special solution versus saline

  This study is testing if a special solution can lower the risk of joint infections after hip replacement surgery compared to regular saline.

  Recruiting at 3 sites Northwell Health · Manhasset, New York and 2 other locations · NCT05519007

• Oral antibiotics for treating bone and joint infections in children

  This study tests if giving only oral antibiotics can effectively treat bone and joint infections in children, compared to the usual method that starts with IV antibiotics.

  Recruiting at 9 sites Phase 4 Murdoch Childrens Research Institute · Kingswood, New South Wales and 10 other locations · NCT04538053

• Using alpha-defensin and synovial proteins to diagnose pediatric septic arthritis

  This study is testing if certain proteins in joint fluid can help doctors better diagnose septic arthritis in children who might have joint infections.

  Recruiting at 2 sites Hospital for Special Surgery, New York · Atlanta, Georgia and 2 other locations · NCT03704766

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.