Collection of gut microbiota samples from patients with bone or joint infections on antibiotic therapy
Constitution Of A Biological Collection From Samples From The Gut Microbiota In Patients Having A Bone Or Joint Infection Treated By A Suppressive Subcutaneous Antibiotherapy With Betalactamine (CARBAMICROBIOTA)
This study is collecting gut bacteria samples from patients with bone or joint infections who are on long-term antibiotics to see how the treatment affects their gut health and the risk of antibiotic resistance.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 26 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Lyon) |
| Trial ID | NCT03550911 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect biological samples from the gut microbiota of patients suffering from bone or joint infections who are being treated with subcutaneous prolonged suppressive antibiotic therapy using betalactamine. The focus is on understanding the impact of this treatment on gut microbiota and the potential development of antibiotic resistance. The study is particularly relevant for patients who cannot undergo optimal surgical interventions due to age or other factors. By analyzing these samples, researchers hope to gain insights into the effectiveness and safety of this treatment approach.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with bone or joint infections who are receiving subcutaneous antibiotic therapy with betalactamine.
Not a fit: Patients who are not undergoing antibiotic therapy or those with infections that are not treatable with betalactamine may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable information on managing bone and joint infections in patients who are not suitable for surgery.
How similar studies have performed: While there is limited data on the specific approach of this study, similar research on gut microbiota and antibiotic resistance has shown promising results in understanding treatment outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients having a bone or joint infection * Patients treated by a suppressive subcutaneous antibiotherapy with betalactamine Exclusion Criteria: * None
Where this trial is running
Lyon
- Centre de référence des infections ostéo-articulaires de Lyon - Hôpital de la Croix-Rousse — Lyon, France (Recruiting)
Study contacts
- Study coordinator: Tristan FERRY, MD, PhD
- Email: tristan.ferry@chu-lyon.fr
- Phone: 04 72 07 11 07
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.