Cognitive stepped care program for adults with brain metastases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, mixed-methods feasibility project enrolling adults with brain metastases, their caregivers, and clinic staff at a specialized brain metastases clinic. Patients will receive routine cognitive symptom screening with a standardized tool and, based on symptom severity, be routed into tiered interventions ranging from education materials to computerized cognitive testing with individualized debriefing, group strategy training, and neuropsychological consultation as needed. Outcomes include measures of feasibility and acceptability, preliminary changes in cognitive symptoms and related questionnaires completed before and after the program, and qualitative feedback from patients, caregivers, and staff. The goal is to refine the intervention and implementation approach for broader use if it proves acceptable and feasible.

Why it matters

Who can join: the full rules

Patients:

Inclusion Criteria:

* Diagnosed with a brain metastasis for any primary cancer
* Receiving follow-up care in the Brain Metastases Clinic
* Adult (≥ 18 years)
* Able to speak, read, and write in English
* Able to provide written informed consent

Exclusion Criteria:

* History of significant developmental/learning disability or psychiatric disorder, acquired neurological disorder (e.g., traumatic brain injury)
* Poor performance status (ECOG ≥ 3)
* Life expectancy \< 3 months

Caregivers:

Inclusion Criteria:

* Self-identified or identified by consenting patient as a primary caregiver for a person with brain metastases receiving follow-up in the Brain Metastases Clinic
* Adult (≥ 18 years)
* Able to speak, read, and write in English
* Able to provide written informed consent

Exclusion Criteria:

• N/A

Staff:

Inclusion Criteria:

* Currently working as a clinician or administrative staff member in the Brain Metastases Clinic
* Adult (≥ 18 years)
* Able to speak, read, and write in English
* Able to provide written informed consent

Exclusion Criteria:

• N/A

Where it's running

• Princess Margaret Cancer Centre, University Health Network
  Toronto, Ontario, Canada Recruiting

Study contacts

• Study coordinator: Samantha Mayo, RN, PhD
• Email: samantha.mayo@uhn.ca
• Phone: 1-437-218-0860

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.