Clinical trial Recruiting at 1 site Observational Ages 18 and up

Clinical characteristics and one-year outcomes of chronically critically ill adults in China

Official title: Clinical Characteristics and Epidemiology of Chronic Critically Ill Patients in China

Run by West China Hospital · NCT07372742 · Data updated 2026-11-12

This project will measure one-year survival and long-term outcomes in adults in China who become chronically critically ill after prolonged ICU stays.

More Critically Ill trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment459 (estimated)
SponsorWest China Hospital
Academic / other
Locations1 site (Chengdu, Sichuan)
StatusRecruiting
StartedMarch 29, 2025
Main results expectedFebruary 1, 2029
Study endsJune 1, 2029
Registry record updatedJanuary 28, 2026
Trial IDNCT07372742 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 treated at the enrolling ICU who stay eight days or more and have tracheotomy, continuous mechanical ventilation >96 hours, multi-organ failure, sepsis, severe trauma, or severe brain injury, and who agree to telephone follow-up.

Probably not a fit

Patients with shorter ICU stays, those who refuse or cannot be reached for follow-up, or those with conditions unlikely to be altered by care-planning changes may not directly benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort will enroll adults at West China Hospital who remain in the ICU eight days or longer and meet criteria for chronic critical illness (for example tracheotomy, prolonged mechanical ventilation, multi-organ failure, sepsis, severe trauma, or severe brain injury). Clinical data will be recorded during the ICU stay and researchers will conduct semi-structured telephone follow-ups to determine one-year mortality and other long-term outcomes. The study will analyze the epidemiology and identify risk factors associated with poor outcomes. No experimental treatments are given; the goal is to describe patterns of illness and outcomes to inform clinical care and future research.

Why it matters

Potential benefit: If successful, the results could help clinicians identify patients at highest risk and guide decisions about post-ICU care and follow-up.

How similar studies have gone: Similar cohort studies in other countries have documented high one-year mortality and persistent disability among chronically critically ill patients, but large-scale data from China remain limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Must meet: Age greater than 18 years old; Stay in ICU for 8 days or more.

Meet any of the following criteria:

Tracheotomy; Continuous mechanical ventilation for over 96 hours; Multiple organ failure; Sepsis or severe infection; Severe trauma; Severe brain injury;

Exclusion Criteria:

\- Refusing to accept follow-up; Patients who have been lost to follow-up;

Where it's running

  • West China Hospital of Sichuan University
    Chengdu, Sichuan, China
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.