Chatbot-assisted family history and cancer risk assessment in genetic counseling

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study uses an AI-powered chatbot to conduct a structured interview by phone, generate a family pedigree and cancer risk assessments, and deliver a provider summary to the clinical team before the genetics visit. The study compares the chatbot’s identification of NCCN criteria for germline testing with the determination made by a certified genetic counselor. It also evaluates the reliability of chatbot-generated pedigrees, the accuracy of Tyrer-Cuzick breast cancer risk estimates, and satisfaction among patients and providers. Eligible participants include adults seeking initial genetics counseling at Roswell Park, with several criteria to ensure english fluency and consent competence. The aim is to determine if chatbot-assisted data collection can streamline genetic counseling workflow and improve access to care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* PATIENT PARTICIPANTS: Age 18 years or greater
* PATIENT PARTICIPANTS: Scheduled as a new patient appointment to see a certified genetic counselor at the Roswell Park Comprehensive Cancer Center (either in person or for a virtual appointment)
* PATIENT PARTICIPANTS: Written and spoken fluency in English
* PATIENT PARTICIPANTS: Able to understand the consenting process and willing to participate in the study
* GENETIC COUNSELOR PARTICIPANTS: Any genetic counselor who sees patients for initial genetics consultation at Roswell Park Comprehensive Cancer Center is eligible to participate in the study

Exclusion Criteria:

* Prior germline genetic testing for a hereditary cancer predisposition
* First or second-degree family member with a known pathogenic variant, likely pathogenic variant, or variant of uncertain significance in a gene associated with cancer predisposition
* Scheduled to see a genetic counselor who has not give

Where it's running

• Roswell Park Comprehensive Cancer Center
  Buffalo, New York, United States Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• HandX-assisted endoscopic nipple-sparing mastectomy (ATHENA I)

  This study tests whether a handheld robotic device called HandX can help surgeons safely perform a minimally invasive nipple-sparing mastectomy with immediate implant reconstruction for women having therapeutic or risk-reducing mastectomy.

  Recruiting Mediterraneo Hospital · Glyfada, Attica · NCT07292246

• Helping families share hereditary cancer risk information and access genetic testing

  This project tries web-based navigation and communication tools to help adults with a known hereditary cancer gene and their adult biological relatives share risk information and make it easier for relatives to get genetic testing.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT06927947

• Improving genetic counseling for at-risk relatives of cancer patients

  This study is testing if talking directly with a healthcare provider about genetic testing results can help at-risk family members of cancer patients get tested more often and feel better about it.

  Recruiting City of Hope Medical Center · Duarte, California · NCT05772130

• Impact of COVID-19 on financial costs for breast cancer surgery patients

  This study looks at how the COVID-19 pandemic has impacted the out-of-pocket costs and financial struggles of breast cancer patients undergoing surgery.

  Recruiting at 4 sites M.D. Anderson Cancer Center · Conroe, Texas and 3 other locations · NCT04169542

• Genetic testing for hereditary cancer in Switzerland

  This study is trying to see if testing family members of people with hereditary breast, ovarian cancer, or Lynch syndrome can help identify those at risk and improve their chances of early detection and management.

  Recruiting at 5 sites University of Basel · Fribourg, Canton of Fribourg and 8 other locations · NCT03124212

• Investigating genetic factors in childhood cancer

  This study is trying to find out if certain genes passed down in families can increase the risk of childhood cancer by looking at samples from kids who have had cancer and their relatives.

  Recruiting St. Jude Children's Research Hospital · Memphis, Tennessee · NCT03050268

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.