Lung ultrasound and lactate at discharge to predict 30-day outcomes after acute heart failure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter, prospective observational cohort study of adults hospitalized with acute decompensated heart failure who are deemed ready for discharge within 24 hours. At discharge, researchers measure the Lung Ultrasound Score to assess pulmonary congestion and draw a resting blood lactate level to gauge tissue perfusion. The study collects demographic data, heart failure phenotype, vital signs, labs, treatments, and hospitalization details to analyze whether the combined LUS and lactate improve short-term risk stratification. The primary endpoint is a composite of heart failure–related readmission or all-cause mortality within 30 days, with secondary endpoints including all-cause readmission, emergency department visits, and time to first event. Follow-up for outcomes is conducted by telephone and medical record review at 30 days.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years.
* Hospitalization for acute heart failure/decompensation (clinical diagnosis + imaging/laboratory tests according to local practice).
* Patient deemed ready for discharge (decision made by the team, discharge within 24 hours).

Exclusion Criteria:

* Septic shock/severe active infection at the time of discharge.
* Hypoxemia or respiratory distress requiring high-flow oxygen/ventilation at the scheduled time of discharge.
* Severe cirrhosis/advanced liver failure.
* Refusal to participate.
* Technical impossibility of LUS.

Where it's running

• Fattouma Bourguiba Hospital of Monastir
  Monastir, Monastir Governorate, Tunisia Recruiting

Study contacts

• Principal investigator: Semir Nouira, Professor — LR12SP18 ,University of Monastir
• Study coordinator: Semir Nouira Nouira, Professor
• Email: semir.nouira.urg@gmail.com
• Phone: +216 73 106 046

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.