Clinical trial Recruiting at 1 site Interventional Ages 50 to 80

Brain Health PRO online program to reduce dementia risk

Official title: The Brain Health PRO Online Risk Factor Reduction Study for The Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia

Run by University of British Columbia · NCT07364019 · Data updated 2026-11-12

This online program tests whether a six‑month lifestyle education plan can help people aged 50–80 who are at risk for dementia reduce their risk factors.

Quick facts

Study typeInterventional
Ages50 Years to 80 Years
SexAll
Enrollment700 (estimated)
SponsorUniversity of British Columbia
Academic / other
Locations1 site (Vancouver, British Columbia)
StatusRecruiting
StartedMay 7, 2026
Main results expectedDecember 31, 2028
Study endsDecember 31, 2028
Registry record updatedMay 19, 2026
Trial IDNCT07364019 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 50–80 with at least one dementia risk factor (e.g., family history, lower education, hypertension, high cholesterol, BMI > 30) who can participate in online assessments and education in English or French.

Probably not a fit

Individuals without access to reliable internet or who are not at increased dementia risk may derive little or no benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults 50–80 at increased dementia risk are randomly assigned to start the Brain Health PRO program immediately or after six months. The intervention uses online education about evidence-based lifestyle changes to lower dementia risk factors and engage participants in brain health actions. All participants have access to the material for 12 months following initial access, and assessments are conducted remotely. The trial aims to see if online education can be practically implemented across a diverse Canadian population to support dementia prevention. Results will inform whether scalable digital lifestyle interventions can contribute to reducing dementia risk.

Why it matters

Potential benefit: If successful, participants may improve modifiable risk factors and gain sustained access to brain health resources that could lower their dementia risk.

How similar studies have gone: Digital, education-based lifestyle interventions have shown promise in reducing risk factors in similar populations, though large-scale evidence specific to online dementia risk reduction is still evolving.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Completion and documentation of the electronic Informed Consent Process (from the participant)
* Sufficient proficiency in English or French to undergo online assessments and participate in an online educational program.
* Technical ability to participate in an online educational program and remote assessments (i.e., regularly have access to a computer or tablet with an internet connection; have access to a desktop or laptop computer with an internet connection at least once every 6 months; ability to send and receive emails; ability to complete online assessments)
* Sufficient vision to participate in an online educational program and complete online cognitive testing
* Ages 50-80
* Classified as being at increased risk of dementia based on at least one of the following:

  * First-degree family history of dementia
  * Education level at or below high school (grade 12 or less)
  * Self-Reported: Hypertension, Hypercholesterolemia, Body Mass Index \> 30 kg/m2 (derived from NIH Metric BMI Calculator), or Physical Inactivity (active is defined as engaging in a minimum of 20- 30 min of physical activity causing sweating and breathlessness, at least 2 times a week)

Exclusion Criteria:

* Individuals who have a clinical diagnosis of Dementia (based on self-report)
* Individuals who are currently participating in or have participated in a past study involving BHPro

Where it's running

  • University of British Colubmia
    Vancouver, British Columbia, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.