Project to identify cognitive impairment and dementia risk using mobility tests
Uppsala-Dalarna Dementia and Gait Project
Dalarna University · NCT05893524
This study is testing a new way to spot early signs of cognitive problems and dementia by combining a mobility test with a verbal task to see if it can help identify those at risk.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 550 (estimated) |
| Ages | 37 Years to 94 Years |
| Sex | All |
| Sponsor | Dalarna University (other) |
| Locations | 2 sites (Falun, Dalarna County and 1 other locations) |
| Trial ID | NCT05893524 on ClinicalTrials.gov |
What this trial studies
The Uppsala-Dalarna Dementia and Gait Project aims to aid in the early identification of cognitive impairment and dementia risk through a novel dual-task test combining the Timed Up-and-Go (TUG) mobility test with a verbal task. This observational study will evaluate the validity, reliability, and predictive capacity of the TUG dual-task (TUGdt) in predicting dementia. Additionally, the project seeks to generate normative reference values from healthy individuals to enhance the understanding of cognitive decline. The research is conducted at Uppsala University Hospital and Falu Hospital in Sweden.
Who should consider this trial
Good fit: Ideal candidates include patients undergoing memory assessments at Uppsala University Hospital or Falu Hospital, as well as cognitively unimpaired individuals with a high MMSE score.
Not a fit: Patients who are unable to walk independently or require a walking aid may not benefit from this study.
Why it matters
Potential benefit: If successful, this project could lead to earlier detection of cognitive impairment and dementia, allowing for timely interventions.
How similar studies have performed: While the approach is innovative, further research is needed to confirm its effectiveness, as similar dual-task methodologies have shown promise but require validation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing memory assessment at at Uppsala University Hospital, Sweden * Patients undergoing memory assessment at at Falu Hospital, Sweden * Cognitively unimpaired individuals with a Mini Mental State Examination (MMSE) score of \> 26 Exclusion Criteria: * Inability to walk three meters back and forth * Inability to rise from a sitting position * Indoor use of a walking aid * Current or recent hospitalization (within the last 2 weeks) * Need of an interpreter to communicate in Swedish
Where this trial is running
Falun, Dalarna County and 1 other locations
- Dalarna University — Falun, Dalarna County, Sweden (COMPLETED)
- Uppsala University — Uppsala, Uppsala County, Sweden (RECRUITING)
Study contacts
- Principal investigator: Anna Cristina Åberg, PhD — Dalarna University
- Study coordinator: Anna Cristina Åberg, PhD
- Email: aab@du.se
- Phone: +4623778082
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Dementia, Dementia, Mixed, Dementia Senile, Dementia of Alzheimer Type, Mild Cognitive Impairment, Subjective Cognitive Impairment, Timed Up-and-Go, TUG, TUG dual-task