Bone Shell Technique vs Ti-PTFE Membrane for Augmenting the Back of the Jaw
Official title: Khoury's Bone Shell Technique Versus Titanium-Reinforced Polytetrafluoroethylene for Augmentation of Horizontal Deficiency in Posterior Mandible (Histomorphometry Analysis): A Randomized Clinical Trial
Run by British University In Egypt · NCT07669792 · Data updated 2026-11-12
This study tests whether Khoury’s Bone Shell technique builds more bone than a non-resorbable Ti-PTFE membrane for people with missing teeth in the back of the lower jaw who want implants.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 16 (estimated) |
| Sponsor | British University In Egypt Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | June 20, 2025 |
| Main results expected | October 2026 |
| Study ends | March 2027 |
| Registry record updated | July 16, 2026 |
| Trial ID | NCT07669792 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with two or more missing posterior mandibular teeth and buccolingual ridge width <4 mm seeking implant restoration.
✕Probably not a fit
Patients with active systemic conditions, smoking, prior ridge grafts at the site, or severe vitamin D deficiency may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares two bone augmentation methods used before dental implants in the posterior mandible. It uses histomorphometric analysis to measure bone gained from each technique. Participants must have two or more missing posterior mandible teeth and a narrow alveolar ridge, with follow-up for implant suitability. The study is conducted at the British University in Egypt and focuses on autogenous and xenograft grafting combined with each device. Outcomes emphasize bone quality and suitability for subsequent implant placement.
Why it matters
Potential benefit: If successful, the approach could improve bone gain and implant readiness for patients with advanced ridge deficiency.
How similar studies have gone: Prior work on guided bone regeneration and membrane techniques has shown variable bone gains; this study tests a direct histologic comparison of two approaches.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Have two or more missing teeth in the posterior mandibular segment. 2. The patients age of 18 and above. 3. The alveolar ridge in the edentulous site of the selected patients will have a buccolingual width of less than 4mm. 4. Sufficient vertical bone height. 5. Free of any local or systemic condition that may contraindicate ridge expansion procedure. Exclusion Criteria: 1. Patients taking any medication that may interfere with bone healing or bone biology. 2. Patients with any systemic disease that may affect bone healing. 3. Any patients with any previous bone grafting procedure at the site of interest. 4. Smokers. 5. Patient's that have been diagnosed with periodontal disease, as sufficient ridge height would be improbable. 6. Patients with significant vitamin D deficiency.
Where it's running
-
The British University in Egypt
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Abdelaziz H. Saad Abdelkarim, Bachelor's Degree
- Email: PG.Abdelaziz92344012@bue.edu.eg
- Phone: +201020690459
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.