Interoceptive Sensitivity and Central Sensitization in Fibromyalgia
Official title: Association Between Interoceptive Sensitivity and Central Sensitization Symptom Burden in Women With Fibromyalgia: A Cross-Sectional Study
Run by Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · NCT07878286 · Data updated 2026-11-12
This study tests how people with fibromyalgia perceive internal bodily signals and whether that relates to their symptom burden.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | Women only |
| Enrollment | 110 (estimated) |
| Sponsor | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Academic / other |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | September 9, 2026 |
| Main results expected | January 15, 2027 |
| Study ends | January 15, 2027 |
| Registry record updated | October 16, 2026 |
| Trial ID | NCT07878286 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 18–65 with fibromyalgia (per 2016 ACR criteria) experiencing widespread pain for at least 3 months and able to complete questionnaires.
✕Probably not a fit
Individuals outside the inclusion criteria or with conditions that prevent completing study assessments may not benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This cross-sectional observational study investigates the relationship between interoceptive sensitivity and central sensitization symptom severity in adults with fibromyalgia. Participants will complete standardized assessments for interoception, pain, fatigue, sleep quality, anxiety, and depression, and the connections among these measures will be analyzed. The goal is to clarify how internal bodily perception relates to fibromyalgia symptoms and to lay groundwork for future longitudinal or interventional work. Interventions used in this study include the Central Sensitization Inventory, the Multidimensional Assessment of Interoceptive Awareness (MAIA-2), the Revised Fibromyalgia Impact Questionnaire, a numeric rating scale for pain, and the Hospital Anxiety and Depression Scale. The study is conducted at Sultan Abdulhamid Han Training and Research Hospital in Istanbul, Turkey, with female adults aged 18–65 who meet diagnostic criteria and consent to participate.
Why it matters
Potential benefit: If successful, results could improve understanding of symptom drivers in fibromyalgia and guide more targeted approaches to managing interoceptive and central sensitization-related symptoms.
How similar studies have gone: Prior work in related areas suggests links between interoception and chronic pain, but this exact cross-sectional focus in fibromyalgia is relatively novel and exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women patients aged 18-65 * Diagnosed with fibromyalgia according to the 2016 ACR criteria * Experiencing widespread pain for at least 3 months * Having the cognitive ability to complete the scales * Having read and signed the informed consent form (ICF) Exclusion Criteria: * Being under 18 or over 65 years old * Pregnancy * Active inflammatory rheumatic disease * Neurological disease * Malignancy * Severe psychiatric disorder * Serious systemic disease such as heart or kidney failure
Where it's running
-
Sultan Abdülhamid Han Eğitim ve Araştırma Hastanesi
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Feyza Nur Yücel, Assoc. Prof.
- Email: dr.fny28@gmail.com
- Phone: (0216) 542 20 00
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.