Music-4-MS: A 12-week music-based program to support thinking skills in people with MS
Official title: A Randomized Controlled Trial of Music-4-MS Compared to Music Listening to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study
Run by University of Texas at Austin · NCT07759115 · Data updated 2026-11-12
A 12-week music-based program is tested to see if it helps cognitive function and mood in people living with multiple sclerosis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 64 (estimated) |
| Sponsor | University of Texas at Austin Academic / other |
| Locations | 1 site (Austin, Texas) |
| Status | Recruiting |
| Started | August 10, 2026 |
| Main results expected | March 2028 |
| Study ends | August 2028 |
| Registry record updated | August 17, 2026 |
| Trial ID | NCT07759115 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with multiple sclerosis (any major MS type) who report cognitive difficulties and have internet access.
✕Probably not a fit
Individuals without MS cognitive impairment or those unable to engage with an online program may see little or no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This feasibility study tests a 12-week music-based eHealth intervention called Music-4-MS for adults with multiple sclerosis. The approach uses music training and listening to engage multiple senses with the goal of supporting cognitive and emotional well-being. Researchers will assess practicality, engagement, and preliminary effects on cognition and mood to inform future larger trials. Participants must have MS, self-reported cognitive issues, and internet access to participate. The study is led by the University of Texas at Austin with collaboration from the National Institute of Nursing Research.
Why it matters
Potential benefit: If successful, the program could offer a non-invasive and engaging option to help preserve or improve cognitive function and mood in MS patients.
How similar studies have gone: Prior cognitive rehabilitation research supports multisensory approaches, but feasibility of a music-based digital intervention in MS is still being explored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed with multiple sclerosis (relapsing remitting, secondary progressive, primary progressive) * Diagnosed more than 6 months prior to starting study * Self-reported cognitive impairment as assessed by having at leased 5 problems "sometimes" or more often on the Perceived Deficits Questionnaire * Read, write, and understand English * Access to internet Exclusion Criteria: * Diagnosed with another neurological condition that causes cognitive impairment * MS exacerbation within the last 30 days * Professional musician (primary source of income)
Where it's running
-
University of Texas at Austin
Austin, Texas, United States Recruiting
Study contacts
- Principal investigator: Carolyn Phillips, PhD — University of Texas at Austin
- Study coordinator: Carolyn Phillips, PhD, RN
- Email: carolyn.phillips@nursing.utexas.edu
- Phone: 512-475-7039
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.