Analyzing Gingival Color to Evaluate Periodontal Treatment Effectiveness
Official title: Application of CIELab Spectrophotometry to Analyze Gingival Color: a New Perspective for Evaluating the Effectiveness of Periodontal Basic Treatment
Run by Second Affiliated Hospital, Zhejiang University, School of Medicine · NCT06698718 · Data updated 2026-11-12
This study is testing if changes in gum color can help show how well treatment works for people with gum disease.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Second Affiliated Hospital, Zhejiang University, School of Medicine Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Status | Recruiting |
| Started | October 18, 2024 |
| Main results expected | March 1, 2025 |
| Study ends | March 1, 2025 |
| Registry record updated | November 21, 2024 |
| Trial ID | NCT06698718 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Han ethnicity patients aged 18 to 65 diagnosed with periodontitis who have not received any periodontal treatment in the last six months.
✕Probably not a fit
Patients with severe cardiac issues, uncontrolled systemic diseases, or those currently on specific medications may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the relationship between gingival color and clinical indicators in patients with periodontitis. It will include 30 patients who have not received any periodontal treatment in the past six months. Participants will undergo periodontal basic treatment, and their gingival crevicular fluid will be analyzed for inflammatory markers before treatment and at 6 and 12 weeks post-treatment. The study aims to correlate these findings with clinical indicators to assess treatment effectiveness.
Why it matters
Potential benefit: If successful, this study could provide a new method for evaluating the effectiveness of periodontal treatments based on objective color analysis.
How similar studies have gone: While the approach of using color analysis in periodontal treatment evaluation is relatively novel, similar studies have shown promise in correlating clinical indicators with treatment outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients of Han ethnicity, aged between 18 and 65 years old, diagnosed with periodontitis 2. I haven't received any periodontal basic treatment, including scaling, scraping, flap surgery, etc., for the past six months 3. The anterior teeth area has not undergone periodontal surgery or coronal restoration within six months 4. The patient has clear thinking, unobstructed communication, and high compliance Exclusion Criteria: 1. Cardiac function levels III and IV 2. Blood pressure\>180/110 mmHG 3. Pregnant women, women in pregnancy or lactation 4. Those who are currently taking anticoagulant drugs, calcium channel blockers, immunosuppressants, angiotensin and other medications, receiving bisphosphonates treatment, or have a history of antibacterial treatment within 3 months 5. Uncontrolled and stable patients with systemic diseases, such as progressive liver diseases, infectious diseases, renal failure, rheumatoid diseases, blood system diseases, osteoporosis, AIDS, mental diseases and diabetes, etc 6. Patients with malignant tumors or undergoing radiotherapy, chemotherapy, and targeted drug therapy 7. Patients with pacemakers who cannot undergo ultrasound therapy 8. Smoking or quitting smoking for less than 5 years 9. Individuals with abnormalities such as pigment deposition and keratinized beads in the front teeth and gums
Where it's running
-
2 nd Affiliated Hospital, School of Medicine, Zhejiang University, China
Hangzhou, Zhejiang, China Recruiting
Study contacts
- Study coordinator: Sun
- Email: weiliansun@zju.edu.cn
- Phone: +86 13757119563
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This observational study compares boron levels and inflammation markers in saliva and gum tissue between people with periodontitis and healthy controls to see if boron relates to gum inflammation.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.