Analyzing genetic mutations in pediatric cardiomyopathy
Pediatric Cardiomyopathy Mutation Analysis
This study is trying to learn more about the genetic causes of heart problems in children with cardiomyopathy to help improve diagnosis and treatment options for them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Sex | All |
| Sponsor | Indiana University Academic / other |
| Locations | 1 site (Indianapolis, Indiana) |
| Trial ID | NCT02432092 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather information from children diagnosed with various forms of cardiomyopathy and their families to better understand the genetic factors involved in this heart condition. By focusing on the molecular genetics of pediatric cardiomyopathy, the study seeks to improve diagnostic accuracy and inform future genetic counseling. The research highlights the need for precise genetic diagnosis, as outcomes in children with cardiomyopathy can vary significantly based on the underlying genetic cause. The findings may lead to enhanced management strategies and novel treatment options for affected individuals.
Who should consider this trial
Good fit: Ideal candidates include children diagnosed with cardiomyopathy and their family members.
Not a fit: Patients without cardiomyopathy or their family members are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved genetic diagnosis and management strategies for children with cardiomyopathy.
How similar studies have performed: Previous studies have shown success in identifying genetic causes of cardiomyopathy in adults, but this approach in pediatric populations is less explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects with cardiomyopathy * Family members of subjects with cardiomyopathy Exclusion Criteria: * Subjects without cardiomyopathy * Family members of subjects without cardiomyopathy
Where this trial is running
Indianapolis, Indiana
- IU School of Medicine — Indianapolis, Indiana, United States (Recruiting)
Study contacts
- Principal investigator: Stephanie Ware, MD, PhD — IU School of Medicine
- Study coordinator: Lindsey Helvaty, BS, BA
- Email: lhelvaty@iu.edu
- Phone: (317) 278-3020
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.