Analyzing dental enamel defects using color measurement techniques

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the analysis of enamel defects, specifically targeting conditions such as Amelogenesis Imperfecta, dental fluorosis, and Molar Incisor Hypomineralization. It employs a spectrophotometer to measure tooth colors as a non-invasive diagnostic tool for early detection of enamel abnormalities. Participants will undergo screening and follow-up visits where dental samples will be collected for biological, structural, and physicochemical analyses. The study aims to enhance understanding of these enamel pathologies and improve diagnostic methods.

Why it matters

Who can join: the full rules

For patients :

Inclusion Criteria :

1. Age between 8 and 55 years old
2. Carrier of one of the following 3 quantitative pre-eruptive enamel anomalies : AIH, dental fluorosis or MIH
3. Information and collection of the non-opposition of the adult patient or of the representative(s) of parental authority present for the minors.

Criteria for non-inclusion :

1. Pregnant or breastfeeding woman
2. Under guardianship or curators
3. Opposition of the minor patient
4. Presenting pre-eruptive anomalies only on the molars (the spectrophotometer can only take pictures of the anterior dental sector (incisors and canines)).
5. Other types of hypomineralization (post-eruptive, of traumatic or infectious origin, idiopathic).
6. Having undergone radiotherapy or chemotherapy inducing dental and periodontal damage.
7. Having systemic abnormalities (unbalanced diseases), haemochromatosis, porphyria
8. Under medication likely to disturb the coloring of the teeth

For witnesses :

Inclusion Criteria :

1. Age between 8 and 55 years old
2. Information and collection of the non-opposition of the adult witness or of the representative(s) of parental authority present for the minors.
3. Free of any anomaly of tooth structure, exogenous dyschromia and carious lesions.

Criteria for non-inclusion :

1. Pregnant or breastfeeding woman
2. Under guardianship or curators
3. Opposition of the minor witness
4. Carrier of a quantitative pre-eruptive enamel anomaly
5. Polycarpus (preventing the diagnosis of amyl hypomineralization)

Where it's running

• Service d'odontologie, Hôpital Pitié-Salpêtrière
  Paris, France Recruiting

Study contacts

• Study coordinator: Sophia HOUARI, MCU-PH
• Email: sophia.houari@aphp.fr
• Phone: 06 12 16 88 35

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.