See if resin infiltration helps mild MIH in kids aged 7–11

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study combines a cross-sectional description of MIH prevalence and risk factors with a controlled clinical trial to compare resin infiltration against control treatments for mild MIH lesions in permanent incisors. The trial will evaluate color change, lesion depth, and aesthetic outcomes over time, using ICON resin infiltration and comparator protocols such as fluoride varnish or observation. Participants are children aged 7–11 with mild MIH and intact incisors, recruited from selected schools in Hanoi and surrounding areas. Outcomes will be analyzed to determine the potential clinical benefits and inform future management guidelines for MIH in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children aged 7 to 11 years.
* Children diagnosed with mild Molar-Incisor Hypomineralization (MIH) according to EAPD criteria on permanent incisors.
* Permanent incisors with intact anatomical shape, showing smooth enamel surfaces or minor defect depth without post-eruptive enamel breakdown (PEB).
* Children and parents/guardians willing to participate and sign the informed consent form.

Exclusion Criteria:

* Children with severe MIH lesions accompanied by post-eruptive enamel breakdown (PEB), atypical restorations, or dental caries.
* Permanent incisors with developmental anomalies, fluorosis, amelogenesis imperfecta, dentinogenesis imperfecta, or severe enamel hypoplasia.
* Teeth undergoing active orthodontic treatment or presenting with fixed orthodontic appliances.
* Non-vital teeth, teeth with symptoms of pulpitis, apical periodontitis, or history of endodontic treatment.
* Children with systemic diseases, chronic physical/mental conditions, or severe uncooperative behavior during dental procedures.

Where it's running

• Hanoi Medical University
  Hanoi, North, Vietnam Recruiting
• National Institute Of Hygiene And Epidemiology
  Hanoi, North, Vietnam Recruiting
• National of Odonto-Stomatology, Hanoi
  Hanoi, North, Vietnam Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.