Analyzing autobiographical memory in Alzheimer's and frontotemporal dementia patients
Autobiographical Specificity in Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia
This study looks at how well people with Alzheimer's and frontotemporal dementia can remember personal memories to better understand their memory challenges.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 62 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Nantes University Hospital Academic / other |
| Locations | 1 site (Nantes) |
| Trial ID | NCT05642351 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the ability of patients with Alzheimer's Disease and behavioral variant frontotemporal dementia to retrieve autobiographical memories. Participants will be invited to recall specific memories, which will then be qualitatively analyzed and categorized into different types of autobiographical retrieval. The study aims to enhance understanding of memory specificity in these conditions, potentially informing future therapeutic approaches. By employing a detailed methodology, the research seeks to provide insights into the nature of memory impairment in affected individuals.
Who should consider this trial
Good fit: Ideal candidates for this study are adults diagnosed with Alzheimer's Disease or behavioral variant frontotemporal dementia who can participate without opposition.
Not a fit: Patients with other psychiatric or neurological disorders, minors, or those under guardianship may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve understanding of memory deficits in Alzheimer's and frontotemporal dementia, potentially leading to better therapeutic strategies.
How similar studies have performed: While studies on memory retrieval in dementia exist, this specific qualitative approach to autobiographical memory analysis is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Alzheimer' disease or avioral variant of frontotemporal dementia * No opposition from the patient to be included in the study * For Alzheimer's patients: a score of more than 24 out of 30 on the Mini Mental State Examination (McKhann et al., 1984) Exclusion Criteria: * Other psychiatric/neurological disorders * Minor patients * Adults under guardianship or protection.
Where this trial is running
Nantes
- EL HAJ Mohamad — Nantes, France (Recruiting)
Study contacts
- Study coordinator: Mohamad EL HAJ
- Email: mohamad.elhaj@univ-nantes.fr
- Phone: 02 40 68 66 60
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.