Advancing genomic medicine using electronic health records

Using Behavioral Economics and Implementation Science to Advance the Use of Genomic Medicine Utilizing an EHR Infrastructure Across a Diverse Health System

NA · University of Pennsylvania · NCT06377033

This study is trying to see if using electronic health records and helpful reminders can get more patients tested for genetic conditions in a way that doctors can easily use.

Quick facts

PhaseNA
Study typeInterventional
Enrollment1000 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Pennsylvania (other)
Locations1 site (Philadelphia, Pennsylvania)
Trial IDNCT06377033 on ClinicalTrials.gov

What this trial studies

This study explores innovative methods to enhance the use of genetic testing in clinical practice by utilizing electronic health records (EHR) and behavioral nudges for both clinicians and patients. It aims to identify patients eligible for genetic testing and evaluate the effectiveness of various nudges in increasing testing rates through a randomized controlled trial involving 230 clinicians. The study seeks to refine these nudges based on stakeholder input and disseminate successful strategies for broader implementation in healthcare settings.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with genetic predisposition, paraganglioma, pheochromocytoma, ALS, or Parkinson's disease.

Not a fit: Patients under 18 years of age or those not diagnosed with one of the specified conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve the integration of genetic testing into routine medical care, leading to better-informed treatment decisions for patients.

How similar studies have performed: Other studies have shown promise in using behavioral nudges and EHR systems to enhance clinical decision-making, suggesting that this approach could be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age or older
* diagnosed with one of the study conditions

Exclusion Criteria:

* Under 18 years of age
* not diagnosed with one of the study conditions

Where this trial is running

Philadelphia, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Genetic Predisposition, Paraganglioma, Pheochromocytoma, ALS, Parkinson Disease, Polyneuropathies, Frontotemporal Dementia, Alzheimer Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.