Advancing genomic medicine using electronic health records
Official title: Using Behavioral Economics and Implementation Science to Advance the Use of Genomic Medicine Utilizing an EHR Infrastructure Across a Diverse Health System
Run by University of Pennsylvania · NCT06377033 · Data updated 2026-11-12
This study is trying to see if using electronic health records and helpful reminders can get more patients tested for genetic conditions in a way that doctors can easily use.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | University of Pennsylvania Academic / other |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Status | Recruiting |
| Started | June 10, 2024 |
| Main results expected | June 30, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | August 14, 2026 |
| Trial ID | NCT06377033 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have been diagnosed with genetic predisposition, paraganglioma, pheochromocytoma, ALS, or Parkinson's disease.
✕Probably not a fit
Patients under 18 years of age or those not diagnosed with one of the specified conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study explores innovative methods to enhance the use of genetic testing in clinical practice by utilizing electronic health records (EHR) and behavioral nudges for both clinicians and patients. It aims to identify patients eligible for genetic testing and evaluate the effectiveness of various nudges in increasing testing rates through a randomized controlled trial involving 230 clinicians. The study seeks to refine these nudges based on stakeholder input and disseminate successful strategies for broader implementation in healthcare settings.
Why it matters
Potential benefit: If successful, this approach could significantly improve the integration of genetic testing into routine medical care, leading to better-informed treatment decisions for patients.
How similar studies have gone: Other studies have shown promise in using behavioral nudges and EHR systems to enhance clinical decision-making, suggesting that this approach could be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older * diagnosed with one of the study conditions Exclusion Criteria: * Under 18 years of age * not diagnosed with one of the study conditions
Where it's running
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Penn Medicine
Philadelphia, Pennsylvania, United States Recruiting
Study contacts
- Principal investigator: Katherine L Nathanson, MD — University of Pennsylva
- Study coordinator: Benita Weathers, MPH
- Email: weathers@upenn.edu
- Phone: 215-573-8860
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.