Clinical trial Recruiting at 1 site Observational Ages 35 to 50

Alpha brain waves and time to wake after anesthesia in adults

Official title: An Observational Prospective Study of Anesthetic Sensitivity Assessed by Alpha Band Power and Its Association With Emergence Time From Sevoflurane General Anesthesia in Young Adults.

Run by University of Chile · NCT07254975 · Data updated 2026-11-12

This study tests whether lower alpha power during anesthesia is linked to longer awakening times in adults undergoing elective general anesthesia.

Quick facts

Study typeObservational
Ages35 Years to 50 Years
SexAll
Enrollment70 (estimated)
SponsorUniversity of Chile
Academic / other
Locations1 site (Santiago, RM)
StatusRecruiting
StartedOctober 30, 2025
Main results expectedAugust 31, 2027
Study endsAugust 31, 2027
Registry record updatedOctober 20, 2026
Trial IDNCT07254975 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 35-50 with ASA I-II undergoing elective surgery and no neurological or psychiatric disorders.

Probably not a fit

Patients with significant comorbidities, neurological conditions, or those on psychotropic or opioid medications may not experience the expected benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study records intraoperative EEG to examine if alpha band power relates to emergence time after stopping sevoflurane anesthesia. Participants are adults aged 35-50 with ASA I-II undergoing elective surgery, monitored with a standard BIS EEG device. Emergence time is precisely measured after cessation of anesthetic gases, and results will indicate whether alpha activity can help predict recovery speed. The study uses a standardized GA protocol and analyzes the relationship between EEG patterns and awakening duration. No intervention beyond routine monitoring is planned.

Why it matters

Potential benefit: If successful, the findings could improve understanding of how brain activity relates to anesthesia recovery and potentially guide personalized anesthetic management.

How similar studies have gone: Prior research suggests alpha power may relate to anesthesia depth and recovery, but this specific association in this population is still being explored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria

* Elective surgery under general anesthesia
* Age 35-50 years
* ASA physical status I-II

Exclusion Criteria

* Neurological or psychiatric disorders
* Use of psychotropic drugs or opioids
* Altered consciousness
* BMI \> 35 kg/m²
* Renal, cardiac, or hepatic dysfunction
* Emergency surgery
* Pregnancy
* Regional anesthesia

Where it's running

  • Hospital Clinico de la Universidad de Chile
    Santiago, Rm, Chile
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.