AIRE: Self-care breathing and activity guidance to prevent complications from acute respiratory infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial tests the AIRE respiratory self-care intervention in adults 60 to 80 receiving primary care for an acute respiratory infection. It is a pilot study to see if recruitment, daily self-reporting, and the intervention delivery are feasible before a larger randomized trial. Participants will follow a 14‑day diary and receive guided breathing and activity recommendations via primary care support. The study focuses on safety, feasibility, and process outcomes rather than efficacy outcomes at this stage.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults of any sex aged 60 to 80 years.
* Clinical diagnosis of an ambulatory influenza-like illness, defined as acute-onset cough with fever or a feeling of fever, plus at least one of the following symptoms: muscle aches, sore throat, or headache. Laboratory confirmation of the causative pathogen is not required.
* Five days or less since the onset of the first symptom.
* Presence of at least one of the following chronic conditions or risk factors: hypertension, dyslipidemia, diabetes mellitus, obesity defined as a body mass index of 30 kg/m² or higher, chronic kidney disease, or current smoking.
* Regular access to and use of WhatsApp.

Exclusion Criteria:

* Need for antibiotic treatment at the initial visit because of an evident or suspected bacterial infection.
* Cognitive impairment that prevents understanding of the study or intervention.
* Cancer under active treatment.
* Physical limitations that prevent performance of the breathing exercises.
* Hospitalization for any cause within the previous 6 months.

Where it's running

• CESFAM Dr. Agustín Cruz Melo
  Santiago, Santiago Metropolitan, Chile Recruiting

Study contacts

• Study coordinator: Manuel A Rain, MSc
• Email: manuel.rain@gmail.com
• Phone: 56 976345940

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.