A network to study severe infections in children in China

Establishment of a Multi-Center Big Data System for Severe Infection and a Collaborative Network on Sepsis in Chinese Children

This study looks at how common severe infections like pneumonia and sepsis are in children in China to see how they can be better diagnosed and treated.

Quick facts

• Study type: Observational
• Enrollment: 5000 (estimated)
• Ages: 29 Days to 18 Years
• Sex: All
• Sponsor: Children's Hospital of Fudan University (Academic / other)
• Locations: 1 site (Shanghai, Shanghai Municipality)
• Trial ID: NCT04955210 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the current situation of severe infections, including pneumonia and sepsis, in children across various regions of China. It will investigate the incidence, prognosis, and disease burden of these conditions while establishing and validating risk prediction and diagnostic models. Additionally, the study will evaluate the effectiveness and safety of different treatment approaches in real-world settings, focusing on various age groups and high-risk factors.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 0 to 18 years diagnosed with severe pneumonia and/or sepsis.

Not a fit: Patients with notifiable infectious diseases or those participating in other clinical trials during the same period may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnosis and treatment strategies for severe infections in children, ultimately enhancing patient outcomes.

How similar studies have performed: Other studies have shown success in similar approaches to understanding severe infections in pediatric populations, indicating potential for valuable insights.

Eligibility criteria

Inclusion Criteria:

1. Children between 0 and 18 years old.
2. Severe pneumonia and/or sepsis.

Exclusion Criteria:

1. notifiable infectious diseases.
2. The researcher believes that he is not suitable to participate in other situations in this study.
3. Participants in other clinical trials in the same period.

Where this trial is running

Shanghai, Shanghai Municipality

• Children's Hospital of Fudan University — Shanghai, Shanghai Municipality, China (Recruiting)

Study contacts

• Principal investigator: Guoping Lu — The Children's Hospital of Fudan University
• Study coordinator: Guoping Lu

Conditions Critical Illness; Severe Sepsis; Sepsis; severe infection