Sponsor or institution
Clinical trials and research at Winifred Masterson Burke Med Res Inst
As of November 12, 2026, Find a Trial lists 14 NIH-funded research projects at this institution, with $30.0 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 14NIH research projects
NIH-funded research (14)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
Investigating how a specific protein influences neuron development in the brain.
This study is looking at how a specific part of the brain helps create different types of nerve cells, focusing on a factor called St18 that helps shape these cells, which could lead to better understanding and treatments for brain-related conditions.
-
How brain-to-spine nerve cells may help restore precise hand and arm movement after spinal cord injury
This work explores whether targeted rehabilitation can guide damaged brain-to-spine nerve cells to rewire and help people with spinal cord injuries regain fine hand and forearm movement.
-
How genes shape brain cells that control movement
This work looks at how genes guide the development of brain cells that control voluntary movement to help people with ALS, spinal cord injury, stroke, or cerebral palsy.
-
Investigating how specific neurons in the entorhinal cortex are affected by Alzheimer's disease.
This study is looking at how certain brain cells in a part of the brain called the entorhinal cortex might be affected in Alzheimer's disease, and it aims to find out if these cells are too active because of other cells being overactive or underactive; by testing special mice, the researchers hope to learn more about h
-
High-dose vitamin B1 (benfotiamine) to reduce harmful sugar-related protein damage in Alzheimer's
Looks at whether high-dose thiamine (benfotiamine) lowers harmful sugar-related protein damage and helps people with Alzheimer's, and whether the common APOE4 gene changes the effect.
-
Investigating how brain activity changes and protein buildup contribute to Alzheimer's disease
This study is looking at how changes in brain activity and protein buildup in a specific area of the brain might lead to Alzheimer's disease, using mice to help us understand what happens early on, which could help us find new ways to prevent or treat the disease.
-
Why brain-to-spine nerve cells lose their ability to regrow during development
This work looks at why the brain-to-spine nerve cells that control movement lose their ability to regrow as we develop, with the goal of helping people with ALS, spinal cord injury, or stroke.
-
Understanding how nerve cells help recover hand movement after spinal cord injury
This study looks at how spinal cord injuries impact the brain's control over hand movements and explores how rehabilitation can help improve these abilities, aiming to find better ways to support recovery for people with these injuries.
-
Understanding how brain cells develop for motor control after injury or disease
This study is looking at how certain brain cells that help control movement develop and connect in people with conditions like ALS and after strokes, with the goal of finding ways to improve recovery and movement for those who are paralyzed.
-
Investigating how high doses of thiamine may help in Alzheimer's disease by reducing harmful compounds.
This study is looking at whether a special form of vitamin B1 called benfotiamine can help improve symptoms for people with Alzheimer's disease, especially those who have a certain genetic risk factor, by reducing harmful compounds in the body.
-
Understanding how nerve cells can regenerate after injury during development
This study is looking at how nerve cells in the spinal cord can heal and grow back after being injured, especially how this ability changes as we grow up, with the hope of finding better ways to help people recover from paralysis caused by strokes or other conditions.
-
Investigating neuron dysfunction in ALS and its impact on motor control
This study is looking at how the loss of certain brain cells affects movement in people with ALS, using mice to learn more about the connections between these cells and the ones that control movement, with hopes of finding new ways to help treat the disease.
-
Benfotiamine for early Alzheimer's disease
This trial tests whether benfotiamine, a form of vitamin B1, can improve memory and slow decline in people with early Alzheimer's disease.
-
Investigating benfotiamine as a treatment for early Alzheimer's disease
This study is looking at whether a vitamin called benfotiamine can help improve memory and brain health in people with early Alzheimer's disease over 18 months, and you'll either get the vitamin or a placebo to see how it works.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.