NIH-funded research NIH-funded research

Co-treated care for substance use and heart infection at UVMMC

Official title: Modeling Contextual Infective Endocarditis and Substance Use Disorder Cotreatment

Funded at University of Vermont & St Agric College · NIH-11599499 · Data updated 2026-11-12

A hospital-based project aims to improve how doctors and teams treat people with both substance use disorder and infective endocarditis during their hospital stay.

More Substance Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Vermont & St Agric College
NIH-funded
Lab location1 site (Burlington, United States)
Project startAugust 1, 2026
Project endJuly 31, 2028
Funding year2026
Award (this year)$220,389
NIH project number5P20GM125498-09
Project IDNIH-11599499 on NIH RePORTER

Who could benefit from this research

Could help

Adults with a history of injection drug use and infective endocarditis who are receiving hospital care.

Less likely to help

Patients without co-occurring SUD or IDU-IE are unlikely to benefit from this co-treatment focus.

What this research studies

This grant supports work at the University of Vermont Medical Center to understand how context, culture, and hospital resources affect co-treatment of substance use disorder and infective endocarditis. The team will use a mix of anthropological and systems-thinking methods to identify barriers and opportunities for integrated care. The goal is to develop practical, context-informed strategies that clinicians can implement to reduce stigma, improve adherence to antibiotics, and prevent readmissions. The project focuses on real-world hospital care and how to adapt practices to better support patients with co-occurring IDU-IE and SUD.

Why it matters

Potential benefit: Better, more compassionate care pathways could reduce readmissions and improve health outcomes for people with IDU-IE and SUD.

How similar studies have gone: Prior hospital-based protocols for co-treatment have been feasible but showed limited impact, highlighting the need for context-informed approaches.

Where this research is happening

  • University of Vermont & St Agric College
    Burlington, United States
    Active

Researchers

  • Principal investigator: Kozelka, Ellen — University of Vermont & St Agric College
  • Study coordinator: Kozelka, Ellen

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.