NIH-funded research R01 grant

Optimizing aerobic fitness and how older adults respond to exercise

Official title: Optimizing Aerobic Fitness and Functional Response to Exercise in Older Adults.

Funded at University of Vermont & St Agric College · NIH-11384658 · Data updated 2026-11-12

This grant tests exercise programs to help older adults with daily activities improve their heart health and physical function after hospital stays.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Vermont & St Agric College
NIH-funded
Lab location1 site (Burlington, United States)
Project startJuly 15, 2024
Project endJune 30, 2029
Funding year2026
Award (this year)$546,687
NIH project number5R01AG084636-03
Project IDNIH-11384658 on NIH RePORTER

Who could benefit from this research

Could help

Older adults, particularly women, with aging-related muscle weakness or disability who participate in or could benefit from cardiac rehabilitation and structured aerobic or resistance training.

Less likely to help

Individuals without functional limitations or those unable to participate in structured exercise may see limited or no benefit.

What this research studies

Older adults who have been hospitalized often lose strength and may struggle with daily tasks. The project focuses on how different aerobic and resistance training approaches, including high-intensity options, affect peak fitness and functional abilities in aging individuals. Researchers will compare multidimensional exercise routines to see which best restores muscle size, strength, and everyday function for those with acquired disabilities. The goal is to identify practical, effective exercise strategies that can be used in cardiac rehabilitation to support healthier aging. The study is conducted through the University of Vermont and an affiliated college, led by Dr. Sherrie Khadanga.

Why it matters

Potential benefit: If successful, older adults could regain more independence and better physical function after hospital stays through improved exercise programs.

How similar studies have gone: Prior CR exercise programs show functional benefits, but this project explores combined multi-modal approaches to address muscle size and strength in older adults.

Where this research is happening

  • University of Vermont & St Agric College
    Burlington, United States
    Active

Researchers

  • Principal investigator: Khadanga, Sherrie — University of Vermont & St Agric College
  • Study coordinator: Khadanga, Sherrie

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.