NIH-funded research R01 grant

Dynamic patterns of oral nicotine pouch use and tobacco transitions in adults

Official title: Dynamic patterns of oral nicotine pouch use and transitions in cigarette and smokeless tobacco use: a fine-grained naturalistic cohort study

Funded at University of Vermont & St Agric College · NIH-11427892 · Data updated 2026-11-12

A long-term study is following adults to understand how people start, switch, or stop using oral nicotine pouches, cigarettes, and other tobacco products.

More Tobacco Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Vermont & St Agric College
NIH-funded
Lab location1 site (Burlington, United States)
Project startSeptember 30, 2026
Project endAugust 31, 2031
Funding year2026
Award (this year)$697,566
NIH project number1R01DA066535-01
Project IDNIH-11427892 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older who use or are at risk of using cigarettes, smokeless tobacco, or oral nicotine pouches.

Less likely to help

Young individuals under 21 or people not using any tobacco products may not directly benefit.

What this research studies

This project tracks adults over several years to map how ONP use changes day-to-day and how it relates to cigarette or smokeless tobacco use. Researchers will collect real-world data to see who uses ONPs, who quits, and who starts or relapses with other products. The study aims to reveal patterns that could inform safer use strategies and public health guidance. Results could help people make informed decisions about tobacco and nicotine products.

Why it matters

Potential benefit: If successful, the findings could guide better cessation strategies and policy decisions to reduce cancer risk related to tobacco use.

How similar studies have gone: There is limited evidence on ONP trajectories; this study addresses a novel area with potential for meaningful insights.

Where this research is happening

  • University of Vermont & St Agric College
    Burlington, United States
    Active

Researchers

  • Principal investigator: Klemperer, Elias M — University of Vermont & St Agric College
  • Study coordinator: Klemperer, Elias M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.