Sponsor or institution

Clinical trials and research at University of Sydney

• 20Clinical trials
• 13NIH research projects
• 8Countries

Newest trials

All recruiting trials (20)

• Comparing exercise, cognitive behavioral therapy for insomnia, and both for chronic musculoskeletal pain with poor sleep

  This project will test whether a 12-month home-based exercise program, CBT for insomnia, or their combination helps reduce pain and improve sleep in adults with chronic low back pain or hip/knee osteoarthritis who have poor sleep.

  Recruiting University of Sydney · San Antonio, Nevada and 3 other locations · NCT07532070

• Integrated healthy lifestyle and pain care for people with musculoskeletal conditions in rural areas

  Aiming to see if an in-person or a virtual, lifestyle-focused pain care program helps rural adults with musculoskeletal pain and lifestyle risks feel less impact from their pain.

  Recruiting at 2 sites University of Sydney · Coffs Harbour, New South Wales and 2 other locations · NCT07173335

• Diet changes to reduce sleepiness in narcolepsy and idiopathic hypersomnia

  This project will try whether a 12-week whole-food ketogenic diet versus an isocaloric standard whole-food diet reduces daytime sleepiness and improves quality of life in adults with narcolepsy or idiopathic hypersomnia.

  Recruiting University of Sydney · Macquarie Park, New South Wales · NCT07006233

• Online interpretation training to reduce pain in people with Type 2 diabetes

  This trial will try an online training (CBM-I) to encourage less pain-focused interpretations and reduce pain in adults with Type 2 diabetes and persistent pain.

  Recruiting University of Sydney · Camperdown, New South Wales · NCT06908486

• Postoperative Lung Function Prediction in Lung Cancer Patients

  This study compares CT ventilation imaging-based predictions of postoperative lung function with the standard anatomically based method in adults with lung cancer undergoing evaluation for surgery.

  Recruiting University of Sydney · Saint Leonards, New South Wales · NCT06494254

• Finding the right steroid dose for acute T cell rejection after kidney or kidney–pancreas transplant

  This trial will test whether lower doses of steroids work as well as higher doses to treat acute T cell–mediated rejection in people who have had a kidney or simultaneous kidney–pancreas transplant.

  Recruiting at 2 sites Phase 3 University of Sydney · Lambton, New South Wales and 29 other locations · NCT06474273

• Ventilation imaging to guide lung radiotherapy in non-small cell lung cancer

  This study tests whether using lung ventilation imaging can help plan radiotherapy for people with stage II–IV NSCLC to reduce lung toxicity.

  Recruiting University of Sydney · St Leonards, New South Wales · NCT06159660

• Healthy lung sparing during radiation therapy for lung cancer

  This trial tests a new CT ventilation imaging approach to guide radiation therapy in lung cancer patients to spare healthy lung and see if it improves quality of life.

  Recruiting Phase 3 University of Sydney · Liverpool, New South Wales · NCT06127654

• Digital self-management package for people with interstitial lung disease

  This study is testing a new smartphone app designed to help people with interstitial lung disease manage their health better and feel improved overall compared to standard care.

  Recruiting at 4 sites University of Sydney · Sydney, New South Wales and 3 other locations · NCT06122233

• Fosfomycin for treating antibiotic-resistant urinary tract infections in children

  This study is testing if fosfomycin can help children with antibiotic-resistant urinary tract infections feel better compared to standard treatments.

  Recruiting at 4 sites Phase 3 University of Sydney · Sydney, New South Wales and 4 other locations · NCT05709028

• MRI-based imaging to guide radiotherapy for glioblastoma

  Doctors are testing whether special MRI techniques can map tumor hypoxia in glioblastoma patients to see if higher radiation doses can be targeted to the most aggressive parts of the tumor.

  Recruiting University of Sydney · St Leonards, New South Wales and 1 other locations · NCT05500612

• Using N-acetylcysteine to help manage alcohol use disorder

  This study is testing if a medication called N-acetylcysteine can help people with alcohol use disorder reduce their drinking and improve their treatment results.

  Recruiting Phase 4 University of Sydney · Sydney, New South Wales and 2 other locations · NCT05408247

• Developing a markerless tracking method for real-time tumor motion measurement during radiation therapy

  This study is testing a new way to track tumor movement during radiation therapy without using markers, to see if it can help doctors target the treatment more accurately for cancer patients.

  Recruiting University of Sydney · Saint Leonards, New South Wales and 3 other locations · NCT05184790

• Using contrast agents to improve liver cancer radiation therapy

  This study is testing if using special contrast agents can help doctors better track liver tumors during radiation therapy for patients who have already received a different treatment.

  Recruiting University of Sydney · Waratah, New South Wales and 4 other locations · NCT05169177

• Real-time imaging for lung cancer radiotherapy

  This study is testing if a new type of real-time imaging can help lung cancer patients get better radiotherapy by improving how accurately doctors can see and target tumors during treatment.

  Recruiting University of Sydney · Blacktown, New South Wales · NCT05030207

• Evaluating treatments for calciphylaxis in kidney failure patients

  This study is testing different treatments for adults with kidney failure who have just been diagnosed with calciphylaxis to see which ones work best.

  Recruiting at 21 sites Phase 3 University of Sydney · Concord, New South Wales and 20 other locations · NCT05018221

• Real-time monitoring of lung tumors during radiotherapy

  This study is testing a new technology that tracks lung tumors in real-time during radiation treatment to see if it can make the treatment more precise for lung cancer patients.

  Recruiting University of Sydney · Melbourne, Victoria · NCT04086082

• Low-dose thrombolytic therapy for heart attack patients

  This study is testing if a low dose of a clot-busting drug can help heart attack patients recover better after their treatment.

  Recruiting at 14 sites Phase 3 University of Sydney · Bankstown, New South Wales and 21 other locations · NCT03998319

• Evaluating the impact of sodium levels in dialysis on heart events

  This study is testing whether using different levels of sodium in dialysis can help reduce heart problems and deaths in people who are on hemodialysis.

  Recruiting at 263 sites Phase 4 University of Sydney · Adelaide and 263 other locations · NCT02823821

• Accelerated versus standard BEP chemotherapy for intermediate and poor‑risk metastatic germ cell tumours

  This trial will test whether giving BEP chemotherapy every 2 weeks instead of every 3 weeks helps males (typically aged 11–50) with intermediate- or poor‑risk metastatic germ cell tumours do better.

  Recruiting at 53 sites Phase 3 University of Sydney · Downey, California and 55 other locations · NCT02582697

NIH-funded research (13)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How a small brain region makes reward-related cues grab attention

  This work looks at how the lateral hypothalamus makes people with substance-use problems notice drug-related cues and become more likely to relapse.

  NIH research University of Sydney · Sydney, Australia · NIH-11494406

• Understanding how alcohol affects the developing brain from teens to older adults

  This project looks at how drinking alcohol during adolescence and beyond changes brain development and behavior over time.

  NIH research University of Sydney · Sydney, Australia · NIH-11415115

• Why prostate cancer affects men of African ancestry differently

  Researchers will compare tumor and blood genomes from men of African ancestry to find genetic, environmental, and microbial factors linked to more aggressive prostate cancer.

  NIH research University of Sydney · Sydney, Australia · NIH-11399700

• Brain tissue bank for alcohol-related brain research

  A biobank provides high-quality brain tissue from people with chronic alcohol use and matched controls to help scientists understand how alcohol affects the brain.

  NIH research University of Sydney · Sydney, Australia · NIH-11397024

• Mapping alcohol's neurobiology from adolescence to adulthood

  A long-term study from the University of Sydney will follow people from adolescence into adulthood to understand how alcohol affects the brain and behavior.

  NIH research University of Sydney · Sydney, Australia · NIH-11363691

• MPL-QS21 adjuvant combo and how it boosts vaccine responses

  This grant explores how a two-adjuvant combo (MPL and QS21) works to strengthen vaccines, with a focus on safety and effectiveness for people, especially older adults.

  NIH research University of Sydney · Sydney, Australia · NIH-11349344

• Improving vaccines for tuberculosis

  This study is working on creating better vaccines for tuberculosis, especially for people at higher risk like those with HIV, by testing different ingredients that help boost the vaccine's effectiveness.

  NIH research University of Sydney · Sydney, Australia · NIH-11196785

• Improving vaccines for tuberculosis

  This study is looking to create better vaccines for tuberculosis, especially for people at higher risk like those with HIV, by testing different ingredients that help boost the vaccine's effectiveness in animals to find the best options for future vaccines.

  NIH research University of Sydney · Sydney, Australia · NIH-11167404

• Brain tissue bank for alcohol-related brain damage

  Collecting donated brain tissue and health information from people with long-term heavy alcohol use and matched controls to help researchers learn how alcohol harms the brain.

  NIH research University of Sydney · Sydney, Australia · NIH-11161583

• Understanding why some people with HIV can temporarily control the virus without medication

  This project looks at why a small number of people with HIV can keep the virus at low levels for months after stopping their medication.

  NIH research University of Sydney · Sydney, Australia · NIH-11141241

• Improving vaccines to prevent tuberculosis

  This study is working on creating better vaccines for tuberculosis, especially for people at higher risk like those with HIV, by testing different combinations of ingredients that boost the immune response to find the most effective ones.

  NIH research University of Sydney · Sydney, Australia · NIH-10919146

• Understanding how the brain influences addiction and behavior towards rewards

  This study looks at how certain brain cells influence learning and behavior around rewards, especially for people dealing with substance-use disorders, to help find new ways to support them in resisting cravings and staying sober.

  NIH research University of Sydney · Sydney, Australia · NIH-10880659

• Improving vaccines to prevent tuberculosis

  This study is working on creating better vaccines for tuberculosis, especially for people at higher risk like those with HIV, by testing different ingredients that help boost the vaccine's effectiveness, so we can find the best options to protect against TB.

  NIH research University of Sydney · Sydney, Australia · NIH-10703854

Quick answers

How many clinical trials run by University of Sydney are recruiting right now?

20, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in Australia (20 trials), New Zealand (4 trials), United States (2 trials), Canada (2 trials), United Kingdom (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 6, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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