Sponsor or institution

Clinical trials and research at University of Mississippi Med Ctr

• 117NIH research projects

NIH-funded research (newest 40 of 117)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding how HTLV-1 hides inside immune cells to drive ATLL

  A research project at the University of Mississippi Medical Center is studying how HTLV-1 makes monocytes and macrophages harbor the virus, with the goal of finding ways to restore the body’s own ability to clear it and slow ATL/ATLL progression.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11590582

• Placental support cells and fetal red blood cell quality in preeclampsia

  This grant studies how placental support cells in preeclampsia affect the development and quality of a baby’s red blood cells.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11545411

• Epigenetic clues to preeclampsia in pregnancy

  This grant explores how epigenetic changes and paternal factors may contribute to preeclampsia, a condition that can affect pregnancy health.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11545399

• Fentanyl use during pregnancy and its effects on mom, placenta, and baby

  This project studies how fentanyl use during pregnancy affects a mother's health, the placenta, and the development of the child.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11454741

• Professional Development Core for Clinical & Translational Research in Mississippi

  A grant to strengthen clinical and translational research training and community-engaged programs in Mississippi to accelerate care for chronic diseases including diabetes and dementia.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11435578

• RS Core: Support for Clinical Research Develop­ment and Population Health in Mississippi

  A patient-facing program to help doctors and researchers design and run clinical, translational, and community health studies more effectively.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11435577

• RDCD Core supports smarter clinical research and data handling

  This grant funds a core service that helps doctors and researchers design better studies, manage data securely, and ensure regulatory compliance to improve care for Mississippians with chronic diseases.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11435576

• Mississippi Community Engagement and Outreach Core (CEO) for Clinical Research

  This grant supports community partnerships and a practice-based research network in Mississippi to improve access to care and community-based research.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11435575

• Health Research Core for Mississippi Clinical and Translational Research

  A central hub in Mississippi coordinates clinical and translational research to grow local expertise, support investigator-led studies, and expand access to trials for people with chronic diseases.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11435574

• Administrative Core for Mississippi Cardiovascular Translational Research Center

  A dedicated Administrative Core supports multi-institutional cardiovascular and chronic-disease research in Mississippi to speed community-engaged translational projects.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11435573

• Mississippi Center for Clinical and Translational Research (MCCTR) at UMMC

  A national-level research program in Mississippi is building a coordinated approach to improve health and reduce chronic diseases, including dementia, by linking hospitals, universities, and community partners.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11435572

• New small-molecule therapy for Huntington's disease aimed at lowering disease-causing protein

  A potential drug candidate called GLYN122 is being developed to reach the brain and lower the harmful huntingtin protein in Huntington’s disease patients.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11428277

• Sex differences in high blood pressure, thinking skills, and kidney function tied to B cells and autoantibodies

  This research looks at how sex and pregnancy-related antibodies may influence high blood pressure, thinking abilities, and kidney blood flow in adults.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11416476

• Perinatal Health and Long-Term Cardiovascular and Metabolic Outcomes Center

  A NIH Center grant funds a Mississippi program to understand how problems during pregnancy affect mothers and children later in life, especially regarding heart, kidney, and metabolic health.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11416351

• Core Resources Core B for Perinatal Cardiorenal Research

  A center grant to keep state-of-the-art equipment and expert help available to researchers studying cardiorenal disease and perinatal health.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11416350

• Perinatal health center to improve outcomes for mothers and babies

  A Mississippi research center is funding Phase 2 work to uncover how conditions before, during, and after pregnancy affect mothers and their children in the long term.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11416349

• Vascular causes of Alzheimer’s disease: a new therapy approach targeting sEH

  This grant tests a vascular-based approach to treat Alzheimer’s disease by blocking an enzyme (sEH) to improve brain blood flow and reduce inflammation in people with AD/ADRD.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11416277

• Understanding how the inner ear patterns its cells to prevent hearing loss

  Researchers are studying how specific genes control the arrangement of cells in the inner ear to help prevent or treat hearing loss in older adults.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11401013

• Endocannabinoid signals in ear development

  A scientist at the University of Mississippi Medical Center is studying how natural cannabis-like signals affect how our inner ear develops, especially the cells that detect sound and balance.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11401008

• Understanding residual hearing after unilateral hearing loss

  This NIH grant explores how the remaining hearing in one ear is affected and what this means for balance and brain processing in adults with unilateral hearing loss.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11401003

• Neurophysiology Core for Balance and Hearing Research

  A research core will provide state‑of‑the‑art tests and models in rodents to study balance and hearing disorders related to Alzheimer’s disease and cognitive aging.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11400997

• Molecular Neuroscience and Imaging Core for Balance and Hearing Research

  A dedicated core hub supports brain and ear research by providing advanced imaging, mouse genetics, and cryopreservation services to researchers and trainees.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11400991

• Administrative Core of the Balance and Auditory Research Center (BARC)

  This grant funds the administrative backbone for a center that aims to advance balance and hearing research through strong governance, mentoring, and sustainability planning.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11400983

• Balance and Hearing Center to Improve Balance and Hearing Health

  A center-based program at the University of Mississippi Medical Center aims to understand why balance and hearing problems happen, so doctors can diagnose and treat them better for people of all ages.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11400980

• Career Enhancement Core for junior investigators in sex differences and women’s health

  A program to help early-career researchers become independent NIH-funded scientists focused on sex differences and women’s health.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11397779

• Leadership Administrative Core for SCORE program

  A leadership and administration core that keeps a multi-year program running smoothly, supports mentors and investigators, and coordinates NIH and university-wide activities.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11397771

• Progesterone-Linked Immune Changes to Help Pregnancies with Preeclampsia

  A safety-focused study will test whether giving a progesterone-derived treatment (17-OHPC) can favorably change the immune and inflammatory signals in pregnant people with preeclampsia.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11397765

• Innate immunity, vascular dysfunction, and hypertension in pregnancy

  This project tests how immune cells in pregnancy may drive high blood pressure and vascular problems during pregnancy and after, with the goal of improving outcomes for mothers and babies.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11397758

• Inflammation, High Blood Pressure, and Mom’s Long-Term Well-Being During Pregnancy

  This project looks at how immune changes during pregnancy-related high blood pressure may affect a mother’s brain health and mood, and how it could influence babies after birth.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11397751

• Adaptive immunity and AT1 receptor antibodies in preeclampsia and effects on offspring

  A $201k, five-year study from the University of Mississippi Medical Center will explore how immune factors and AT1 receptor antibodies contribute to preeclampsia and its long-term effects on children.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11397744

• Causes of sex differences in children born from pregnancies affected by preeclampsia

  This grant aims to understand why male and female offspring differ in health outcomes when the mother has preeclampsia, and to explore potential treatments to improve long-term cardiovascular and brain health for these children.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11397742

• MS-ISPCTN pediatric clinical trials network site (Cycle 3)

  A Mississippi pediatric site is continuing to participate in a national network of pediatric trials to help children’s health.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11394339

• Anti-Inflammation and Macrophage Fuel Use After a Heart Attack in Diabetes

  This project looks at how immune cells fuel their activity after a heart attack, especially in people with diabetes, to find new ways to reduce heart damage.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11386392

• Children's of Mississippi Newborn Care Network

  This effort helps the Children's of Mississippi NICU join a national network to improve care and outcomes for high‑risk newborns and families in Mississippi.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11376513

• How cocaine memories differ in women and men

  This work looks at whether brain memory circuits that drive cocaine craving act differently in females than males to help people trying to stay abstinent.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11376172

• How the flu affects the heart and body signals

  This project looks at how flu changes heart function and blood markers from infection through recovery in healthy and obese people and how antiviral drugs may change those effects.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11376171

• How sleep changes tiny brain connections in memory and emotion centers

  This project looks at how sleep reshapes small connections in brain areas tied to emotion and memory to help people with psychiatric conditions like schizophrenia and PTSD who have sleep and memory problems.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11376170

• Oxytocin as a potential therapy for endocrine problems in cocaine use disorder

  A study looking at whether oxytocin could help women with cocaine use disorder manage their hormonal dysfunction and reduce cocaine use.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11366328

• Building mouse models for a new SEND mRNA delivery system

  This project is developing a natural cell-based way to carry therapeutic mRNA into target cells, with the goal of making gene and mRNA therapies safer and more effective for people with genetic diseases.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11361271

• Home blood pressure program adapted for rural Mississippi

  A program helps adults in rural Mississippi manage high blood pressure using home monitoring and a smartphone-based virtual coach.

  NIH research University of Mississippi Med Ctr · Jackson, United States · NIH-11356259

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