Sponsor or institution
Clinical trials and research at University of Massachusetts Boston
As of November 12, 2026, Find a Trial lists 3 clinical trials run by University of Massachusetts Boston that are recruiting, in United States. There are also 34 NIH-funded research projects at this institution, with $15.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 34NIH research projects
- 1Country
Newest trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| How age, sex, and a handgrip affect heart–vessel communication during low blood pressure | — | Boston, Massachusetts | Recruiting | Apr 22, 2025 |
| Home cycling to lower blood pressure and improve thinking and walking in people with MS and high blood pressure | — | Boston, Massachusetts | Recruiting | Aug 15, 2024 |
| Tai Chi for older adults with multisite chronic pain and fall risk | — | Boston, Massachusetts | Recruiting | Oct 15, 2018 |
All recruiting trials (3)
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How age, sex, and a handgrip affect heart–vessel communication during low blood pressure
We will test whether simulated low blood pressure with and without a handgrip exercise changes how the heart and blood vessels communicate in healthy young and older men and women.
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Home cycling to lower blood pressure and improve thinking and walking in people with MS and high blood pressure
This trial will test whether 12 weeks of home-based cycling can lower blood pressure and improve thinking and walking in people with multiple sclerosis who have high blood pressure compared with a home stretching program.
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Tai Chi for older adults with multisite chronic pain and fall risk
This study tests whether a 24-week Tai Chi program helps reduce pain and fall risk in older adults who have multisite pain and have fallen before or use an assistive device.
NIH-funded research (34)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Low-cost, image-guided photodynamic therapy for oral lesions in low-resource settings
A field-tested system combines simple imaging with targeted light-based therapy to screen and treat pre-malignant and malignant oral lesions in low-resource areas.
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How histone variants evolved to shape DNA regulation in yeast and fruit flies
Scientists study how changes in histone proteins, the helpers that package DNA, affect how cells control genes and DNA repair in yeast and fruit flies.
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Partnership to Bridge Gaps in Cancer Research and Education between UMass Boston and Harvard Cancer Center
A collaborative program between UMass Boston and the Harvard Cancer Center aims to close gaps in cancer research, education, outreach, and infrastructure to benefit diverse communities.
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Maintaining male fertility through RNA binding proteins
This grant aims to understand how RNA binding proteins help sperm stem cells in males stay healthy and continue producing sperm, using zebrafish as a model to inform potential fertility improvements.
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Low-cost camera-and-therapy system for oral cancer screening and guided light therapy in low-resource areas
A team is developing an affordable, easy-to-use system that screens for oral cancer and guides light-based therapy in people in low-resource settings.
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Stopping therapy-resistant prostate cancer by blocking FOXA2 and AP-1
This research looks at whether blocking a protein switch called FOXA2 and its partner AP‑1 can stop or reverse prostate cancers that no longer respond to hormone therapy.
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Tai Chi for Pain and Balance in Older Adults
A long-term Tai Chi program is being tested to help older adults with chronic multisite pain feel less pain and improve thinking, walking, and balance, potentially reducing falls.
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Overcoming Barriers to Focused Brain Stimulation with TIS in Humans
A study to test a noninvasive brain stimulation method called transcranial temporal interference stimulation (TIS) to safely modulate deep brain targets in people with brain disorders.
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How photoreceptor subtypes make color vision work in fruit flies
Researchers are studying how different eye cells in fruit flies develop to see colors, which could help us understand human color vision problems.
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Signaling networks that shape organs and tissues in development
A scientist-led project uses fruit flies to map how key signaling pathways control organ growth and tissue patterning, with potential relevance to human brain and cancer biology.
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Affordable camera-guided light treatment for early mouth lesions
This project pairs a low-cost handheld mouth camera, cloud-based AI image reading, and a topical light-activated drug to find and treat early and pre-cancerous oral lesions, with a focus on low-resource settings.
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How the SETD7 protein helps stop prostate cancer growth and treatment resistance
This project looks at how a protein called SETD7 helps keep prostate cancer from growing and from becoming resistant to hormone-based treatments.
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Understanding how salamanders regrow limbs
This research explores how axolotl salamanders naturally regrow lost limbs to learn why human cells struggle to regenerate.
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How BRCA2 problems lead to DNA damage and higher cancer risk
This project looks at how BRCA2 mutations cause DNA damage in cells from people with BRCA2 mutations to find early changes that can lead to breast and ovarian cancer.
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Improving Brain Stimulation for Neurological Conditions
This project explores a new, non-invasive way to stimulate deep brain areas to help people with neurological and psychiatric conditions that haven't responded to other treatments.
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Understanding how young children think about the future
This study is looking at how kids aged 3 to 4 use their memories to think about and plan for things that might happen in the future, helping us understand how their thinking skills grow as they get older.
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Targeting specific proteins to combat treatment resistance in advanced prostate cancer
This study is looking at how two specific proteins help advanced prostate cancer become resistant to standard hormone treatments, with the goal of finding new ways to effectively treat patients who are struggling with this tough condition.
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Investigating how SETD7 helps prevent prostate cancer progression and therapy resistance
This study is looking at how a protein called SETD7 affects prostate cancer and how it might change the way well-known treatments work, with the goal of finding better options for patients dealing with advanced prostate cancer.
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Understanding how Wnt5 signaling affects blood cell formation
This study is looking at how a specific signaling process affects the growth and development of blood cells, using fruit flies to help us understand how this might relate to blood disorders like leukemia, so we can learn more about how to keep blood stem cells healthy and functioning properly.
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Creating new medicines using high pressure techniques
This study is looking at how using high pressure can help make important ingredients for medicines more efficiently, which could ultimately benefit both drug makers and patients.
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Understanding how nutrition affects the body's internal clock
This study looks at how what we eat affects our body's internal clock, using a type of fungus to learn more about how these changes happen, which could help us understand health issues related to our daily rhythms and nutrition in people.
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Understanding how BRCA2 mutations lead to cancer
This study is looking at how normal cells turn into cancer cells in people with BRCA2 mutations, which raise the risk of breast and ovarian cancers, to find ways to prevent cancer from developing.
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Exploring HPV vaccination attitudes among Cape Verdean parents
This study is looking at what helps or hinders Cape Verdean parents in deciding to get the HPV vaccine for their kids, aiming to understand their views and experiences so we can boost vaccination rates and help prevent HPV-related cancers.
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Improving brain stimulation techniques for treatment-resistant patients
This study is exploring a new, gentle way to stimulate the brain that could help people with tough neurological and mental health issues who haven't found relief with regular treatments, starting with tests on monkeys before moving on to humans to see how it affects movement.
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Understanding how we balance remembering and using visual information
This study looks at how people choose between remembering things and using visual hints in their daily lives, helping us understand how we make decisions and use our memory in everyday tasks.
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Understanding Brazilian immigrant parents' knowledge and behaviors regarding their children's oral health
This study looks at how Brazilian immigrant parents think about and take care of their young children's teeth, especially when it comes to preventing cavities, and it aims to understand the challenges they face in getting dental care and how their culture influences their dental habits.
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Improving early intervention services for children with autism
This study is testing a fun and friendly way to help young children with Autism Spectrum Disorder by training caregivers to use a special play technique, so that more kids under 3 can get the support they need to thrive.
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How early microbial exposure affects immune system development
This study is looking at how the germs we encounter early in life can shape our immune system and overall health later on, using African Clawed Frogs to help us understand how this works, which might eventually help people with autoimmune diseases.
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New antioxidants targeting mitochondria to treat preeclampsia
This study is looking at new ways to help pregnant women with preeclampsia by creating special antioxidants that can target the energy centers in their cells, aiming to reduce stress and improve blood flow during pregnancy.
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How exercise affects kidney blood flow in African American adults
This study is looking at how exercise affects blood flow to the kidneys in African American adults, who are more likely to face heart and kidney health issues, to help understand how staying active might protect their kidney health over time.
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Understanding how BRCA1 mutations lead to breast cancer using a new mouse model
This study is looking at how breast cancer starts in women with BRCA1 mutations, using a special mouse model to find out what happens in breast cells before tumors form, which could help develop better treatments and prevention for those at risk.
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Understanding how stem cells help maintain male fertility
This study is looking at how certain cells in the testes help make sperm, using zebrafish to understand the environment they need to thrive, and the goal is to find new ways to help men who have trouble producing sperm.
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Understanding how salamanders regrow their limbs
This study is looking at how salamanders, like the Mexican Axolotl, can regrow their limbs to find new ways to help people who have lost limbs, by figuring out how to make human cells do the same.
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Investigating how a protein involved in cell energy can help improve insulin resistance in obesity
This study is looking at how a protein called Drp1 might be causing insulin resistance in people with obesity, and it aims to find new ways to help improve insulin sensitivity, which could lead to better treatments for those dealing with weight-related health issues.
Quick answers
How many clinical trials run by University of Massachusetts Boston are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.