Understanding how nutrition affects the body's internal clock
Official title: Deciphering metabolic and cellular effectors of nutritional compensation in the circadian clock
Funded at University of Massachusetts Boston · NIH-11019031 · Data updated 2026-11-12
This study looks at how what we eat affects our body's internal clock, using a type of fungus to learn more about how these changes happen, which could help us understand health issues related to our daily rhythms and nutrition in people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Massachusetts Boston NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | February 1, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $361,454 |
| NIH project number | 1R35GM157067-01 |
| Project ID | NIH-11019031 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions affected by circadian rhythms, such as sleep disorders, metabolic issues, or certain cancers.
✕Less likely to help
Patients with acute conditions unrelated to circadian rhythms or nutrition may not benefit from this research.
What this research studies
This research investigates how the body's circadian clock, which regulates various biological processes, is influenced by nutritional factors. By studying a fungal model organism, Neurospora crassa, the researchers aim to uncover the molecular mechanisms that allow the circadian clock to adapt to changes in nutrient levels. The findings could provide insights into how similar processes work in human cells, potentially leading to better understanding of health conditions related to circadian rhythms and nutrition.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for conditions influenced by circadian rhythms, such as sleep disorders, metabolic syndromes, and certain cancers.
How similar studies have gone: Previous research has shown success in understanding circadian biology through model organisms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Massachusetts Boston
Boston, United States Active
Researchers
- Principal investigator: Kelliher, Christina — University of Massachusetts Boston
- Study coordinator: Kelliher, Christina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.