Sponsor or institution
Clinical trials and research at University of Connecticut Storrs
As of November 12, 2026, Find a Trial lists 191 NIH-funded research projects at this institution, with $76.9 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 191NIH research projects
NIH-funded research (newest 40 of 191)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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New sequencing machine to boost veterinary genomics at CVMDL
A new high-throughput DNA/RNA sequencer will be acquired and put into use at the Connecticut Veterinary Medical Diagnostic Laboratory to improve how we study and diagnose animal diseases.
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How IL-10 changes mast cells in allergic reactions
This work looks at how the immune signal IL-10 changes mast cells and their responses in people with food allergies.
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Optimizing a just-in-time intervention to help MSM access chemsex harm-reduction services
A smartphone app-driven approach tests personalized, timely support to help men who have sex with men access chemsex harm-reduction services and reduce HIV risk.
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Understanding how vagus nerve stimulation helps stroke recovery to guide better treatments
This NIH grant uses computer models to figure out how brief, task-timed vagus nerve stimulation affects the brain after stroke and helps movement recovery.
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Targeting c-Myc DNA with next-generation nucleic acid tools in aggressive B-cell lymphomas
This grant tests a new way to slow or stop aggressive B-cell lymphomas by directly targeting the c-Myc gene in patients and model systems using advanced nucleic acid analogs.
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Soft, bendable 3D electronics and microfluidic micro-labs for drug screening in engineered tissues
A team at the University of Connecticut is building a soft, 3D electronic and microfluidic platform to grow human organoids and test drugs safely and accurately.
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Dyslexia, stress, and brain inflammation in kids: how biology and daily life shape reading
This NIH grant explores why some children with dyslexia have different reading outcomes by studying stress, inflammation, and brain signals in kids as they learn to read over a school year.
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Restoring T-cell Immunity in Older Adults with Stem-Cell Derived Thymic Cells
Researchers aim to help older adults have a stronger immune system by using stem-cell techniques to rebuild thymic cells that support T-cell development.
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Conversation and language in autistic teens
This project uses real-world and standardized language measures to understand how autistic teens communicate in conversations and how conversational success emerges with different partners.
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Predicting How Real-World Noise Affects Speech Understanding
Aims to improve our understanding of how people, especially older adults and those with hearing loss, understand speech in everyday noisy environments by using advanced models of natural background sounds.
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Understanding how multiple health problems cluster in aging people with HIV
This grant looks at how social factors and multiple health conditions come together to affect aging in people living with HIV.
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Understanding why young men stop PrEP early so they stay protected
A study to learn why men ages 18–35 stop taking PrEP before it’s needed and how to help them stay on it, with a focus on pills and injections.
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PBPK-based predictors for long-acting injectable suspensions
Researchers will build computer models to predict how long-acting injectable suspensions release medicine in the body, helping ensure effective and safe dosing for patients.
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Tracking brain changes during reading help in kids with and without reading trouble
Kids with typical development and those with reading disabilities may show brain changes as they receive reading help, and this study watches those changes over time.
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Non-inferiority comparison of live vs. self-guided remote lifestyle programs
A study tests whether two remotely-delivered lifestyle programs (one with real-time coaching and one that participants lead themselves) produce similar weight loss.
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Glial signaling and breathing in Rett syndrome
Aims to understand how brain support cells (glia) in Rett syndrome affect breathing and whether IGF-1 related signals can improve it.
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Robust Multimodal AI for Breast Cancer Screening
Aiming to improve breast cancer screening with advanced AI that analyzes 3D mammograms to tailor and speed up accurate results for adult women.
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How the Toxoplasma parasite moves cargo inside its cells
Researchers are looking at how the Toxoplasma parasite moves materials inside its cells to better understand ways to stop or treat infections.
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Couples-based weight loss with a mobile app
A couple-focused weight loss program delivered through a mobile app that helps partners support each other to lose weight together.
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Smartphone support to reduce chemsex harms for men who have sex with men
This project uses a smartphone app to send timely, personalized messages and links to harm-reduction services to help men who have sex with men stay safer during chemsex.
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Cytoskeleton and cell suicide: how actin helps control apoptosis
A study in human cells will explore how actin filaments and related proteins influence programmed cell death after DNA damage.
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DNA-inspired materials to safely deliver RNA inside cells for cartilage health
A new, computer-designed biomaterial aims to deliver RNA therapies into cells to treat cartilage diseases.
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Predicting how reading support will work for kids with reading disability
A school-based study will look at which factors help children with reading disabilities respond to reading interventions and how to tailor support for different kids.
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Inhibitory Cell Types and Circuits in the Lateral Hypothalamus
Researchers are studying how inhibitory neurons in the lateral hypothalamus control arousal, motivation, sleep, feeding, and memory to better understand brain function and disorders.
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Vet-LIRN: Strengthening animal health testing and outbreak response at a Connecticut veterinary lab
A Connecticut veterinary lab is expanding its testing and data capabilities to help detect and respond to animal health threats faster.
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Optimizing HIV prevention for people who inject drugs on PrEP
A study to help people who inject drugs and are starting MOUD use improved HIV prevention info and PrEP adherence through targeted support.
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Understanding extra chromosomes using a fruit fly model
This NIH grant supports research to learn how extra chromosomes arise and behave, using a Drosophila model to inform human cancers and developmental disorders, with patient impact in mind.
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Tunable brush-like polymers to improve how implants interact with tissues
A scientist team is creating advanced, bio-friendly brush-like polymer coatings to better control how implanted materials behave in the body and interact with cells.
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Parent-focused program to help remove penicillin allergy labels in kids
A parent-friendly web tool helps families and their child’s pediatrician review and safely remove incorrect penicillin allergy labels.
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Label-free digital cytopathology with UV-ptychography for tissue analysis
A new, dye-free imaging method uses ultraviolet light to map cell nuclei and proteins in tissue quickly, helping doctors make faster decisions.
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A biomarker-based way to quantify visceral pain in IBS
A new approach aims to measure visceral pain in IBS patients with an objective multimodal electrophysiological index to improve drug and non-drug treatments.
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Deep learning to clean CPR artifacts so AEDs can decide quickly
A deep learning method will clean up ECG signals during CPR to help AEDs make faster, more accurate shock decisions for people with out-of-hospital cardiac arrest.
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Behavioral economics approach to keeping weight off after weight loss
A team at the University of Connecticut is testing a two-arm behavioral economics program to help adults with obesity maintain weight loss and reduce related health risks.
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Enabling oral drugs: smarter ways to make medicines that dissolve and get absorbed
This grant aims to develop smarter formulation methods to help drugs with poor solubility or low absorption reach patients more reliably.
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Universal vaccine approach to prevent leptospirosis across humans and animals
A scientific team is working to develop a single vaccine that could protect people and animals from many strains of leptospirosis.
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Targeting specific BET proteins to reduce cocaine-seeking behavior
A patient-friendly look at a research project that tests highly selective BET protein inhibitors to help reduce cocaine-seeking behaviors.
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Injectable cell-free piezoelectric scaffold to treat OA in large animals
A new scaffold that generates electrical signals when it’s pressed could help repair knee cartilage in advanced osteoarthritis, tested in large animal models.
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How parental genomes shape cell identity and cancer risk
Researchers are studying how the two copies of each chromosome from mom and dad are packaged in cells and how this affects development and cancer risk.
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Enhanced delivery of therapeutic nucleic acids using DNA-surfactant conjugates
Aims to make therapeutic nucleic acids more effective by improving how they reach the inside of cells.
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Understanding how animal microbiomes are regulated and connected to health
Researchers study how different microbiomes in a model animal, the Hawaiian bobtail squid, are controlled and how they influence health, development, and the immune system, with potential clues for human health.
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