NIH-funded research R01 grant

Optimizing a just-in-time intervention to help MSM access chemsex harm-reduction services

Official title: Optimizing a Just-in-Time Adaptive Intervention to Increase Uptake of Chemsex Harm Reduction Services in MSM: A Micro-randomized Trial

Funded at University of Connecticut Storrs · NIH-11455243 · Data updated 2026-11-12

A smartphone app-driven approach tests personalized, timely support to help men who have sex with men access chemsex harm-reduction services and reduce HIV risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Storrs
NIH-funded
Lab location1 site (Storrs-Mansfield, United States)
Project startJuly 15, 2024
Project endApril 30, 2029
Funding year2026
Award (this year)$69,846
NIH project number3R01DA061661-03S1
Project IDNIH-11455243 on NIH RePORTER

Who could benefit from this research

Could help

MSM who engage in chemsex and own a smartphone with internet access in Malaysia.

Less likely to help

MSM who do not use smartphones or are not at risk for chemsex-related harms.

What this research studies

This project uses a micro-randomized trial to deliver context-driven prompts and resources through a smartphone app to MSM who engage in chemsex. The goal is to find when and how to push harm-reduction help so it fits naturally into users’ real-life moments. It targets spontaneous risk periods and aims to minimize burden while maximizing willingness to engage with proven harm-reduction strategies. The study is conducted among Malaysian MSM and will inform scalable digital interventions for reducing HIV transmission in this population.

Why it matters

Potential benefit: If successful, the app could provide timely, tailored support that reduces risky chemsex behaviors and lowers HIV transmission risk.

How similar studies have gone: Prior JITAI work shows promise in other health areas, but this is among the first to apply JITAI for chemsex harm reduction.

Where this research is happening

  • University of Connecticut Storrs
    Storrs-Mansfield, United States
    Active

Researchers

  • Principal investigator: Shrestha, Roman — University of Connecticut Storrs
  • Study coordinator: Shrestha, Roman

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.