NIH-funded research R01 grant

Deep learning to clean CPR artifacts so AEDs can decide quickly

Official title: A deep learning artifact removal method for CPR continuity throughout the shock decision in AEDs

Funded at University of Connecticut Storrs · NIH-11345432 · Data updated 2026-11-12

A deep learning method will clean up ECG signals during CPR to help AEDs make faster, more accurate shock decisions for people with out-of-hospital cardiac arrest.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Storrs
NIH-funded
Lab location1 site (Storrs-Mansfield, United States)
Project startJune 1, 2025
Project endMarch 31, 2029
Funding year2026
Award (this year)$696,353
NIH project number5R01HL173935-02
Project IDNIH-11345432 on NIH RePORTER

Who could benefit from this research

Could help

Adults with out-of-hospital cardiac arrest or related ECG data during CPR who could benefit from better AED decision-making.

Less likely to help

Patients without OHCA or those not encountering CPR artifacts in their data may see no direct benefit.

What this research studies

This project will collect CPR artifact data from defibrillators and hospital patients to train a deep learning model. The goal is to produce an algorithm that can accurately analyze ECG during chest compressions without pausing CPR. By reducing unwanted motion noise, the AED can provide timely shocks when indicated, potentially improving survival. Collaboration with U-M and Massachusetts General Hospital will help build a robust dataset and validate the approach.

Why it matters

Potential benefit: If successful, the method could enable more continuous CPR with timely, accurate shock decisions, improving outcomes after cardiac arrest.

How similar studies have gone: Prior work struggled with CPR-induced artifacts; this project advances a data-driven approach and builds on previous attempts with mixed results.

Where this research is happening

  • University of Connecticut Storrs
    Storrs-Mansfield, United States
    Active

Researchers

  • Principal investigator: Chon, Ki H — University of Connecticut Storrs
  • Study coordinator: Chon, Ki H

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.