NIH-funded research R21 grant

Understanding how multiple health problems cluster in aging people with HIV

Official title: Characterizing phenotypes of chronic disease among people aging with HIV in the United States

Funded at University of Connecticut Storrs · NIH-11411008 · Data updated 2026-11-12

This grant looks at how social factors and multiple health conditions come together to affect aging in people living with HIV.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Storrs
NIH-funded
Lab location1 site (Storrs-Mansfield, United States)
Project startJune 1, 2026
Project endMay 30, 2028
Funding year2026
Award (this year)$450,928
NIH project number1R21AG099752-01A1
Project IDNIH-11411008 on NIH RePORTER

Who could benefit from this research

Could help

Adults living with HIV who are aging and experiencing multiple chronic health conditions.

Less likely to help

Individuals without HIV or without multimorbidity may not be directly impacted by this study’s findings.

What this research studies

People aging with HIV often face several chronic illnesses at the same time, and these problems don’t occur in isolation. The study uses a syndemic approach to map how social adversity and biological factors interact to shape disease patterns and accelerated aging. By combining social data with health records, researchers aim to identify clusters of conditions that could guide better, personalized care. The goal is to find actionable insights that help clinicians tailor interventions for aging with HIV.

Why it matters

Potential benefit: Could lead to more personalized care plans that address multiple conditions together rather than one at a time.

How similar studies have gone: Previous work suggests multimorbidity is common in aging with HIV, but this project seeks to define health- and social-factor-driven clusters more precisely.

Where this research is happening

  • University of Connecticut Storrs
    Storrs-Mansfield, United States
    Active

Researchers

  • Principal investigator: Bulled, Nicola — University of Connecticut Storrs
  • Study coordinator: Bulled, Nicola

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.