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Clinical trials and research at Medstar Health Research Institute

• 20Clinical trials
• 22NIH research projects
• 2Countries

Newest trials

All recruiting trials (20)

• Rotating hinge vs condylar constrained knee implants in revision knee replacement

  This study tests whether rotating hinge knee implants perform similarly to condylar constrained implants when used to revise knee replacements in adults.

  Recruiting at 2 sites Medstar Health Research Institute · Washington D.C., District of Columbia and 1 other locations · NCT07818343

• Patient and caregiver perspectives on bladder instillations for urinary symptoms

  This project talks with adults who have neurogenic bladder and their caregivers to see what they prefer and experience with bladder instillations of Lactobacillus, gentamicin, or both.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT07390591

• Collared versus collarless femoral stems for primary total hip replacement

  This trial will test whether adding a collar to a femoral stem reduces sinking (subsidence) and lowers fracture risk in adults having an uncemented total hip replacement for osteoarthritis.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT07337642

• Virtual reality cognitive behavioral therapy for chronic cancer pain

  This project tests whether a virtual reality program that delivers cognitive behavioral therapy can help adults with chronic cancer pain feel less pain than a two-dimensional tablet program.

  Recruiting at 2 sites Medstar Health Research Institute · Washington D.C., District of Columbia and 1 other locations · NCT07318519

• Intravesical Lactobacillus crispatus for urinary health in people with neurogenic bladder

  This study will test whether putting Lactobacillus crispatus into the bladder can help reduce urinary symptoms and urinary tract infections in adults with neurogenic lower urinary tract dysfunction who use intermittent catheters.

  Recruiting Early Phase 1 Medstar Health Research Institute · Washington D.C., District of Columbia · NCT07308808

• Preemptive rimegepant for predictable trigger-induced migraine in adults

  This study will test whether taking a 75 mg dose of rimegepant before a known trigger can prevent migraine attacks in adults who reliably get trigger-induced migraines.

  Recruiting Phase 4 Medstar Health Research Institute · McLean, Virginia · NCT07301008

• Virtual reality for cancer pain relief and opioid reduction

  This project will try virtual reality headsets with adults who have chronic moderate-to-severe cancer pain and take opioids to see if it lowers pain and opioid needs.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT07228377

• Diagnostic journey and treatment disparities for adults with spinal muscular atrophy at MedStar Health

  This project will see how adults with spinal muscular atrophy in the MedStar Health system experienced diagnosis, access to approved SMA therapies, and barriers to care.

  Recruiting Medstar Health Research Institute · Washinton, District of Columbia · NCT07223489

• Genitourinary microbiome before and after Botox bladder injections in postmenopausal women

  We're trying to see if the bacteria in the urine change in postmenopausal women with overactive bladder before and four weeks after Botox bladder injections.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT07025044

• Does minimally invasive fibroid removal change whether fallopian tubes are open?

  This study will test if fallopian tubes are open before and after minimally invasive fibroid removal in people having myomectomy.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT06988774

• Comparing a vibrating pelvic floor device to traditional vaginal dilators for treating entry dyspareunia

  This study is testing whether a new vibrating pelvic floor device can help women with pain during sex feel better compared to using traditional vaginal dilators.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT06840314

• Paraffin Wax plus Exercise for Improving Joint Movement in Burn Scars

  This study will test whether adding paraffin wax to exercise-based scar rehab helps adults with burn scars that cross a joint improve joint range of motion and function.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT06786884

• Using a hand exoskeleton to help stroke patients regain hand function

  This study tests if a special hand device can help stroke patients get better use of their hands again by using it both in clinics and at home.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT06786858

• Comparing wound healing methods in breast reduction surgery

  This study is testing if a special type of wound treatment helps women heal better after breast reduction surgery compared to regular bandages.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT06725459

• Using voice technology to improve post-surgery care for gastrointestinal cancer patients

  This study is testing whether a voice technology system can help improve the recovery and care of patients after surgery for gastrointestinal cancer compared to standard care.

  Recruiting at 2 sites Medstar Health Research Institute · Baltimore, Maryland and 1 other locations · NCT06190730

• Registry for patients with coronary microvascular disease

  This study is creating a database to collect information from people with coronary microvascular disease to help researchers learn more about the condition and improve treatments.

  Recruiting at 3 sites Medstar Health Research Institute · Washington D.C., District of Columbia and 2 other locations · NCT05960474

• Comparing Lactobacillus Rhamnosus GG with saline bladder wash for preventing UTIs in spinal cord injury patients

  This study is testing if a special probiotic combined with a saline bladder wash can help prevent urinary tract infections in people with spinal cord injuries.

  Recruiting Phase 2 Medstar Health Research Institute · Washington D.C., District of Columbia · NCT05230511

• Using Regenerative Peripheral Nerve Interfaces to treat painful neuromas after hand or finger amputation

  This study is testing a new surgery called Regenerative Peripheral Nerve Interfaces to see if it can help reduce pain from nerve issues in people who have had fingers or hands amputated.

  Recruiting Medstar Health Research Institute · Baltimore, Maryland and 1 other locations · NCT05008185

• Survey of patients who fail screening for mitral valve interventions

  This study is trying to learn more about patients who aren't eligible for a specific heart valve procedure to help improve future treatments for mitral valve disease.

  Recruiting at 16 sites Medstar Health Research Institute · Phoenix, Arizona and 15 other locations · NCT04736667

• Long-term follow-up on aortic valve replacement function

  This study looks at how well transcatheter and surgical aortic valves work over time in patients who had these procedures more than three years ago.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT03002272

NIH-funded research (22)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Glucose and brain health: how blood sugar and metabolism affect Alzheimer's risk in a diverse group

  This study follows adults 21 and up to see how long-term blood sugar control and metabolic signals relate to the development of Alzheimer's disease and related dementias.

  NIH research Medstar Health Research Institute · Columbia, UNITED STATES · NIH-11448411

• W-PrEP: clinic-level steps to help women get PrEP for HIV prevention

  A clinic-level program helps healthcare teams better offer and support PrEP for women to prevent HIV.

  NIH research Medstar Health Research Institute · Columbia, UNITED STATES · NIH-11334633

• Investigating cardiovascular disease in Native American populations

  The Strong Heart Study is a long-term project that looks at heart health in Native Americans by following two groups of people over many years to learn more about heart disease and its causes.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11286716

• Investigating how glucose levels affect the risk of Alzheimer's disease

  This study is looking at how blood sugar levels might affect the risk of developing Alzheimer's and related memory problems, and it's for anyone interested in understanding how managing glucose could help protect their brain health.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11261900

• Voice-activated symptom monitoring after gastrointestinal cancer surgery

  A voice-activated system will help people recovering from gastrointestinal tumor surgery report symptoms and get timely follow-up, focusing on reducing gaps for Black and Hispanic patients.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11260237

• Investigating heart health through the Strong Heart Study.

  The Strong Heart Study is looking for people to help us learn more about heart health and how to take better care of it, so if you're interested in sharing your health information and getting involved, you can be part of a team working to improve heart care for everyone!

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11215037

• How blood sugar levels relate to Alzheimer's risk in a diverse group of older adults

  This project looks at how different patterns of blood sugar over time relate to memory problems and dementia risk in older adults from many racial and ethnic backgrounds.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11146533

• Improving social support and fairness in care for minority cancer survivors in Washington, DC

  This project links breast and prostate cancer survivors in Washington, DC to social needs screening, community health worker support, and anti-racism training in clinics to improve quality of life and social connection.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11142940

• Using virtual reality to help manage chronic pain in cancer patients

  This study is exploring a new virtual reality device that helps cancer patients manage their chronic pain by taking them to relaxing virtual environments, and it aims to see how well this fun and calming tool works alongside regular pain treatments.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11115251

• Improving medication safety for children using electronic health records

  This study is working on a new tool to help doctors give the right medicine doses to kids based on their weight, making sure it's easy to use in hospitals and clinics, so that fewer kids get the wrong amount of medicine.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11061208

• Understanding barriers to screening for domestic violence in emergency departments

  This study is looking at how healthcare workers can better spot and help women experiencing domestic violence, especially during the COVID-19 pandemic, so they can provide better support when women come to the emergency room for care.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11057740

• Using algorithms to analyze movement data for recovery after wrist fractures

  This study is looking at how smart technology can track your arm movements while you recover from a wrist fracture, helping doctors understand your healing better and make more informed treatment choices.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11054086

• Using AI to help doctors reduce paperwork in primary care

  This study is looking at how smart AI tools can help your primary care doctor spend less time on paperwork and more time with you, making their job easier and improving your care.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11038097

• Using voice technology to improve recovery after GI cancer surgery

  This study is looking at how a voice-assisted system can help patients recover better after gastrointestinal cancer surgery by keeping track of their symptoms from home, especially for those from different backgrounds who may not always get the best care.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11017626

• Using virtual reality to detect early signs of cognitive decline

  This study is exploring how a fun virtual reality maze can help spot early signs of memory problems in people who might be at risk for Alzheimer's Disease, so we can find ways to help them sooner.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-10990110

• Improving colorectal cancer screening for underserved populations

  This study is all about helping Black individuals get screened for colorectal cancer more often, as they are at higher risk, by providing support and guidance through the healthcare system to make the process easier and more accessible.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-10933504

• Improving how we diagnose health conditions in outpatient care.

  This study is looking at how to make sure everyone gets the right diagnosis in outpatient care, especially for those who might not have the same access to healthcare, so that all patients can feel confident they’re getting the best care possible.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-10931551

• Improving safety in telehealth for patients with chronic conditions

  This study is all about making virtual healthcare visits safer for people with chronic conditions by finding and fixing safety issues, and it involves working together with doctors and tech experts to come up with better solutions for your care.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-10923892

• Improving the accuracy of medical diagnoses through patient involvement

  This study is all about making sure doctors get the right diagnoses by working closely with patients and their families to share important information that might be missing, so everyone can feel safer and more confident in their healthcare.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-10923866

• Improving health and wellbeing for minority cancer survivors in Washington, DC

  This study is looking to help Black cancer survivors by connecting them with community resources that can support their social needs and improve their quality of life, while also providing training to help healthcare workers better understand and address the challenges these survivors face.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-10852791

• Improving HIV prevention services for women

  This study is all about making it easier for women in Washington, D.C. to access PrEP, a medication that helps prevent HIV, by tackling issues like stigma and cost, and it aims to create better support systems to help women feel more comfortable using these services.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-10686097

• Improving patient safety by analyzing safety event reports

  This study is working on new computer tools that can help hospitals understand safety reports better, so they can spot potential dangers and keep patients safe before any harm happens.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-10633121

Quick answers

How many clinical trials run by Medstar Health Research Institute are recruiting right now?

20, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (20 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 1, Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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