Using virtual reality to detect early signs of cognitive decline

Validation of a Virtual Reality Floor Maze Test to Detect Early Signs of Cognitive Impairment

NIH-funded research Medstar Health Research Institute · NIH-10990110

This study is exploring how a fun virtual reality maze can help spot early signs of memory problems in people who might be at risk for Alzheimer's Disease, so we can find ways to help them sooner.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMedstar Health Research Institute NIH-funded
Lab location1 site (Hyattsville, United States)
Project IDNIH-10990110 on NIH RePORTER

What this research studies

This research investigates the use of a virtual reality floor maze test to identify early signs of cognitive impairment, particularly in individuals at risk for Alzheimer's Disease. Participants will navigate through virtual mazes while their gait and navigational skills are assessed, providing valuable data on cognitive function. The study aims to validate this innovative approach as a sensitive and specific marker for cognitive decline, allowing for earlier intervention and treatment. Participants will undergo neuropsychological testing followed by the VR maze assessment to gather comprehensive cognitive data.

Who could benefit from this research

Good fit: Ideal candidates include cognitively normal adults at low risk and higher risk of developing Alzheimer's Disease, as well as individuals with amnesic mild cognitive impairment.

Not a fit: Patients with advanced cognitive impairment or those who are unable to participate in virtual reality assessments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection of cognitive impairment, allowing for timely interventions that may slow the progression of Alzheimer's Disease.

How similar studies have performed: Other research has shown promise in using virtual reality for cognitive assessments, suggesting that this approach could be effective in detecting early cognitive decline.

Where this research is happening

Hyattsville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.