Investigating how glucose levels affect the risk of Alzheimer's disease

Glucose homeostasis and the risk of Alzheimer's disease and Alzheimer's disease related dementias in the Multi-Ethnic Study of Atherosclerosis

NIH-funded research Medstar Health Research Institute · NIH-11261900

This study is looking at how blood sugar levels might affect the risk of developing Alzheimer's and related memory problems, and it's for anyone interested in understanding how managing glucose could help protect their brain health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedstar Health Research Institute NIH-funded
Lab location1 site (Hyattsville, United States)
Project IDNIH-11261900 on NIH RePORTER

What this research studies

This research explores the relationship between glucose homeostasis and the risk of developing Alzheimer's disease and related dementias. By examining a diverse group of participants from the Multi-Ethnic Study of Atherosclerosis, the study aims to identify how different glucose levels and dysglycemia may contribute to cognitive decline. The research will analyze neurocognitive markers to better understand the mechanisms linking glucose metabolism and Alzheimer's disease. This could provide insights into potential preventive strategies for at-risk individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with varying glucose levels, particularly those at risk for type 2 diabetes or cognitive decline.

Not a fit: Patients who do not have any glucose metabolism issues or those already diagnosed with advanced Alzheimer's disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new prevention strategies for Alzheimer's disease, particularly for individuals with glucose metabolism issues.

How similar studies have performed: Previous research has indicated a link between glucose metabolism and cognitive decline, suggesting that this approach may yield valuable insights.

Where this research is happening

Hyattsville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.