Investigating how glucose levels affect the risk of Alzheimer's disease
Official title: Glucose homeostasis and the risk of Alzheimer's disease and Alzheimer's disease related dementias in the Multi-Ethnic Study of Atherosclerosis
Funded at Medstar Health Research Institute · NIH-11261900 · Data updated 2026-11-12
This study is looking at how blood sugar levels might affect the risk of developing Alzheimer's and related memory problems, and it's for anyone interested in understanding how managing glucose could help protect their brain health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medstar Health Research Institute NIH-funded |
| Lab location | 1 site (Hyattsville, United States) |
| Project start | September 30, 2021 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $724,004 |
| NIH project number | 7R01AG070881-03 |
| Project ID | NIH-11261900 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with varying glucose levels, particularly those at risk for type 2 diabetes or cognitive decline.
✕Less likely to help
Patients who do not have any glucose metabolism issues or those already diagnosed with advanced Alzheimer's disease may not benefit from this research.
What this research studies
This research explores the relationship between glucose homeostasis and the risk of developing Alzheimer's disease and related dementias. By examining a diverse group of participants from the Multi-Ethnic Study of Atherosclerosis, the study aims to identify how different glucose levels and dysglycemia may contribute to cognitive decline. The research will analyze neurocognitive markers to better understand the mechanisms linking glucose metabolism and Alzheimer's disease. This could provide insights into potential preventive strategies for at-risk individuals.
Why it matters
Potential benefit: If successful, this research could lead to new prevention strategies for Alzheimer's disease, particularly for individuals with glucose metabolism issues.
How similar studies have gone: Previous research has indicated a link between glucose metabolism and cognitive decline, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Medstar Health Research Institute
Hyattsville, United States Active
Researchers
- Principal investigator: Mongraw-Chaffin, Morgana Lee — Medstar Health Research Institute
- Study coordinator: Mongraw-Chaffin, Morgana Lee
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.