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Clinical trials and research at Masonic Cancer Center, University of Minnesota

• 33Clinical trials
• 1New in 30 days
• 1Country

Newest trials

All recruiting trials (33)

• Understanding NK Cell Function in Prostate Cancer Across Races

  This study tests whether natural killer (NK) cells behave differently in prostate cancer patients of diverse racial backgrounds by analyzing blood and tissue samples.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT07910019

• Adapt NK cells for high-risk AML bridging to stem cell transplant

  This study tests an allogeneic NK cell infusion with a brief IL-2 boost in adults with relapsed or refractory AML to see if treatment can help prepare for a future stem cell transplant.

  Recruiting Phase 1/2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT07591649

• FT536 injection for recurrent WHO Grade 4 astrocytoma

  This will try a single intratumoral dose of FT536, an off-the-shelf engineered NK‑cell therapy, in adults undergoing repeat surgery for recurrent Grade 4 astrocytoma.

  Recruiting Phase 1 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT07560865

• GTB-5550 treatment for people with advanced solid tumors.

  This Phase 1 trial tests GTB-5550, a B7-H3-targeting natural killer (NK) cell engager, in adults with advanced solid tumors who have exhausted or are ineligible for standard treatments.

  Recruiting Phase 1 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT07541573

• Reduced-intensity donor stem cell transplant with treosulfan/fludarabine and post-transplant cyclophosphamide for leukemia and MDS

  This trial tests a lower-intensity donor stem cell transplant using treosulfan plus fludarabine with post-transplant cyclophosphamide to try to reduce toxicity and prevent graft-versus-host disease in people aged 2–75 with acute leukemias or myelodysplastic syndromes.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT07493538

• UNTOLD: Survey on Unmet Needs After Ovarian Cancer

  This project will ask people who have had ovarian cancer to complete a one-time survey (and some a follow-up interview) to learn about ongoing concerns and unmet needs.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT07070726

• Bortezomib combined with CPX-351 for newly diagnosed TP53‑mutated acute myeloid leukemia

  This trial tests whether adding the proteasome inhibitor bortezomib to CPX‑351 helps adults with newly diagnosed TP53‑mutated AML tolerate treatment and improve remission and survival.

  Recruiting Phase 1/2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT07008638

• Donor transplant for high risk blood disorders

  This study is testing if a stem cell transplant from a matched sibling can help people with high-risk blood disorders like sickle cell disease and thalassemia feel better.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06872333

• Tafasitamab with lenalidomide and rituximab for newly diagnosed follicular and marginal zone lymphoma

  This trial will test whether adding tafasitamab to rituximab and lenalidomide is safe and helps people newly diagnosed with follicular lymphoma or marginal zone lymphoma.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06792825

• Direct tumor injection of a modified adenovirus for pancreatic cancer

  This study is testing a new treatment that uses a modified virus injected directly into pancreatic tumors to see if it is safe for people with localized pancreatic cancer.

  Recruiting Phase 1 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06693986

• Cell-based therapy for Duchenne Muscular Dystrophy

  This study is testing a new cell-based treatment for people with Duchenne muscular dystrophy to see if it is safe and helps improve muscle function.

  Recruiting Phase 1 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06692426

• GTB-3650 treatment for high-risk myeloid malignancies

  This study is testing a new treatment called GTB-3650 to see if it can help adults with tough-to-treat blood cancers like acute myeloid leukemia feel better and respond to therapy.

  Recruiting Phase 1 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06594445

• Rural Smokers Quit: Testing Different Ways to Help People Live Smoke-Free

  This study tests different quit-smoking resources with rural adults to see which methods help them stop smoking.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06584929

• Culturally aligned digital smoking cessation program for American Indians

  This study is testing a new online program designed to help American Indian people quit smoking by using methods that respect their cultural values.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06544811

• Early detection of cognitive side effects from immunotherapy

  This project tests whether an automated toolkit called SALSA can find early cognitive side effects in adults receiving CAR-T immunotherapy.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06414278

• Hematopoietic cell transplant for severe blood disorders

  This study is testing a new way to prepare patients with severe blood disorders for a stem cell transplant to see if it can improve their recovery and reduce complications.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06412497

• Comparing two pain relief methods after pancreas surgery

  This study is testing whether a new way of giving pain relief after pancreas surgery works just as well as the traditional method, to help patients feel better with fewer risks.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06411795

• Combination of Pembrolizumab and BEAM for treating relapsed Hodgkin Lymphoma

  This study is testing if giving Pembrolizumab before and after a stem cell transplant can help people with relapsed Hodgkin Lymphoma feel better and have better outcomes.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06377540

• Investigating how acetaldehyde contributes to oral cancer development

  This study is trying to see how drinking alcohol affects the development of oral cancer in healthy people and those with Fanconi anemia by looking at samples like saliva and urine.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT05973656

• Stem cell transplant using a specific preparative regimen for blood cancers

  This study is testing a new way to prepare for a stem cell transplant using a special combination of medications and radiation to see if it helps people with acute leukemia who are in remission.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT05805605

• T cell receptor depletion for blood cancer treatment

  This study is testing a new way to treat blood cancers by using a special treatment before a stem cell transplant to see if it helps both kids and adults do better after the procedure.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT05735717

• Examining environmental toxicant exposure in firefighters

  This study is trying to see how exposure to harmful chemicals during firefighting affects firefighters by collecting urine samples before and after they fight fires.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT05643014

• Peptide Alarm Therapy for advanced or metastatic solid tumors

  The team will try injecting Peptide Alarm Therapy directly into tumors alongside standard IV PD‑1/PD‑L1 drugs for adults whose advanced or metastatic solid tumors progressed after prior treatments, including prior PD‑1/PD‑L1 therapy.

  Recruiting Phase 1 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT05338658

• Exercise, lung, and heart fitness in young survivors of heart transplant, childhood leukemia, and premature lung disease

  This project tests non-invasive exercise and breathing tests to see how well 8–25-year-olds who survived childhood leukemia, were born with chronic lung disease of prematurity, or had a heart transplant tolerate and perform during physical activity.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT05025774

• Combining microbiota therapy with durvalumab and chemotherapy for lung cancer

  This study is testing if adding a special gut treatment to standard chemotherapy and durvalumab can help people with advanced lung cancer feel better and improve their treatment results.

  Recruiting at 9 sites Phase 2 Masonic Cancer Center, University of Minnesota · Phoenix, Arizona and 9 other locations · NCT04105270

• Registry for understanding Adrenoleukodystrophy

  This study is collecting health information and samples from people with Adrenoleukodystrophy to better understand the disease and find ways to improve treatment.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT03789721

• Transplantation for inherited bone marrow failure disorders

  This study is testing a new way to do stem cell transplants for people with inherited bone marrow failure disorders to see if it can help them recover faster and reduce the risk of infections without needing extra medication.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT03579875

• Hematopoietic stem cell transplant for blood cancers

  This study is testing two different ways of doing stem cell transplants for people with blood cancers to see which method works better and is safer.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT03314974

• Auto stem cell transplant for lymphoma patients

  This study tests if a stem cell transplant after chemotherapy can help people with Hodgkin and non-Hodgkin lymphomas, including those with HIV, who are in remission.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT03125642

• Myeloablative chemotherapy and stem cell rescue for high-risk neuroblastoma

  This study is testing a new chemotherapy approach followed by a stem cell rescue to see if it helps children with high-risk neuroblastoma after their initial treatment.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT02605421

• Treatment for graft failure after stem cell transplant

  This study is testing a new treatment for patients who have had a stem cell transplant and are experiencing graft failure, to see if a combination of medications and radiation can help the donor cells take hold in their body.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT02161783

• Second or greater stem cell transplant using reduced intensity conditioning

  This study is testing a gentler approach to give a second or more stem cell transplant to patients with blood disorders who didn't get enough benefit from their first transplant to see if it helps them recover better.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT01666080

• Infusion of unlicensed umbilical cord blood cells for treatment

  This study is testing whether infusing unlicensed umbilical cord blood cells can help people with lymphatic diseases or blood cancers recover after their treatment.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT01451502

Quick answers

How many clinical trials run by Masonic Cancer Center, University of Minnesota are recruiting right now?

33, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 13, Phase 1: 6, Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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