Examining environmental toxicant exposure in firefighters
Official title: Evaluate the Exposure to Toxicants Emitted During a Structural Fire Assessed by Urinary and Buccal Cell Biomarkers Found in Firefighters.
Run by Masonic Cancer Center, University of Minnesota · NCT05643014 · Data updated 2026-11-12
This study is trying to see how exposure to harmful chemicals during firefighting affects firefighters by collecting urine samples before and after they fight fires.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Masonic Cancer Center, University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Status | Recruiting |
| Started | February 1, 2020 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | March 12, 2026 |
| Trial ID | NCT05643014 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are firefighters, both career and volunteer, who are over 18 years old and can provide consent.
✕Probably not a fit
Patients currently diagnosed with cancer or those who have used tobacco in the past year may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study collects biomarker samples from firefighters before and after exposure to combustion emissions during structural fires. The aim is to assess the levels of toxicants, specifically focusing on substances like PAH, 1-HOP, PheT, and SPMA. Participants will provide urine samples to evaluate their exposure to these harmful substances, contributing to a better understanding of the health risks associated with firefighting. The study is designed to gather data without any interventions or treatments.
Why it matters
Potential benefit: If successful, this study could enhance knowledge about the health risks firefighters face due to toxic exposure, potentially leading to improved safety protocols.
How similar studies have gone: While this study focuses on a specific population, similar observational studies have shown success in understanding exposure risks in occupational settings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Firefighter (career or volunteer) * Over 18 years of age * Able to provide written voluntary consent Exclusion Criteria: * Unwilling to provide a pre and post-exposure urine sample * Current cancer diagnosis * Tobacco use within the last 1 year (verified by urinary TNEs)
Where it's running
-
Masonic Cancer Center
Minneapolis, Minnesota, United States Recruiting
Study contacts
- Study coordinator: Joni Jensen
- Email: jense010@umn.edu
- Phone: 612-624-5178
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.