Sponsor or institution
Clinical trials and research at Mainehealth
As of November 12, 2026, Find a Trial lists 3 clinical trials run by Mainehealth that are recruiting, in United States. There are also 56 NIH-funded research projects at this institution, with $34.9 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 56NIH research projects
- 1Country
Newest trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Cannabis use in cancer patients: keeping a cancer cannabis journal on a mobile app | — | Scarborough, Maine | Recruiting | Jul 28, 2025 |
| Examining Neuregulin and EGF Signaling in the Human Heart | — | Portland, Maine | Recruiting | Jun 30, 2016 |
| Investigating inflammation and metabolism after cardiac arrest | — | Portland, Maine | Recruiting | Jan 27, 2016 |
All recruiting trials (3)
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Cannabis use in cancer patients: keeping a cancer cannabis journal on a mobile app
This study tests how cancer patients who use cannabis can track their use and experiences using a smartphone app.
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Examining Neuregulin and EGF Signaling in the Human Heart
This study is trying to see how certain proteins in the heart affect special cells that help keep the heart healthy in people who are having heart surgery.
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Investigating inflammation and metabolism after cardiac arrest
This study looks at how inflammation and metabolism change after cardiac arrest to see if they affect recovery and brain health in patients.
NIH-funded research (newest 40 of 56)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Predicting which kids will grow into obesity using early-life data
Aimed at kids 0-11, this project uses early health data and biology to forecast obesity risk so parents and doctors can act early.
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Energy metabolism changes in smooth muscle cells and aortic disease progression
Aims to understand how energy use in smooth muscle cells affects the progression of aortic aneurysm and dissection in people with aortic diseases.
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MaineHealth Cancer Care Network reaches patients where they live
A Maine-based program aims to bring cancer care closer to home by coordinating care across local hospitals and clinics for adults and children with cancer.
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Improving care for opioid use disorder in the ICU
This project helps hospital staff in intensive care units provide better care for patients with opioid use disorder.
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PFAS exposure in kids: how early chemicals affect puberty and bone health
This NIH grant studies how common PFAS chemicals in children’s blood might delay puberty and affect bone health, using data from a large pediatric cohort.
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Ceftaroline-meropenem combo to beat MRSA in cystic fibrosis
A new combination antibiotic approach is being tested to help people with cystic fibrosis who have MRSA infections that resist standard treatments.
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Enhancing Community Drug Checking to Prevent Overdoses in Rural New England
A community-based program in rural Maine and New Hampshire tests a navigator-led drug checking approach to help people who use drugs make safer choices and reduce overdoses.
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Pilot Project Program for public health research in northern New England
A pilot funding program supports researchers in northern New England to develop public health projects aimed at preventing and managing chronic diseases.
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Tracking and Evaluation Core for a rural health research network
This grant funds a Tracking and Evaluation Core to help a regional clinical and translational research network measure progress, improve programs, and share lessons with rural communities.
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Translational Research Technologies Core (TRTC) for faster, practical biomedical advances
This grant supports shared, cutting-edge research resources to help rural-region investigators move lab findings toward real patient improvements.
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Community Engagement and Outreach Core
A program that strengthens how researchers work with patients and communities to translate basic science into real-world health improvements in northern New England.
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Biostatistics and Research Design Support Core for clinical investigators
A core team helps doctors and scientists use advanced statistics, data methods, and computational tools to run better clinical studies.
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Professional Development Core for clinical researchers in northern New England
This grant supports education, training, and mentorship so clinicians and researchers in northern New England can do high-quality clinical research that benefits local communities.
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Administrative Core for Northern New England Clinical and Translational Research Network
A program to strengthen clinical research infrastructure in rural Maine, New Hampshire, and Vermont so doctors can better test and apply new treatments for chronic diseases.
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Northern New England Clinical and Translational Research Network
A regional research network in Maine and Vermont is building long-term infrastructure to connect primary care with major universities so that community health problems like cancer, cardiovascular disease, and diabetes can be addressed more effectively.
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Strategies to reduce weight stigma and support diabetes care for adults with type 2 diabetes
A patient-facing program explores how reducing weight stigma and using self-affirmation can help adults with type 2 diabetes adopt healthier habits and better manage blood glucose.
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Proteomics and Lipid Profiling Core for cardiometabolic research
A core lab at MaineHealth helps scientists study proteins and fats in mouse and human tissues to understand cardiometabolic diseases.
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Histopathology and Microscopy Core serves tissue analysis needs
A core facility helps researchers at MaineHealth analyze tissue samples using histology and microscopy, supporting many studies and publications.
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Physiology Core supports metabolic measurements for many projects
A facility that helps researchers measure metabolism and body health in animals and cells, to advance multiple health-related projects.
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Administrative and Professional Development Core for COBRE Breathing New Life into Metabolism Research
A core leadership grant to help researchers at MaineHealth grow, collaborate, and keep up-to-date with state-of-the-art science in metabolism and adipose biology.
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Phase II COBRE on Metabolic Networks and Regulation of Fat and Bone Biology
A Phase II NIH grant supports a center focused on how fat tissue, bone health, and neural inputs regulate metabolic networks, with aims to grow research capacity and help people affected by metabolic diseases.
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Environmental Influences on Child Health Outcomes in Maine (ECHO-ME)
A rural Maine pediatric health program aims to carry out kid-focused clinical trials to improve access and care for children, especially in underserved areas.
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Understanding how bone marrow fat cells influence multiple myeloma progression
A patient-facing overview of a grant studying how fat cells in the bone marrow interact with multiple myeloma cells and affect disease behavior.
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Transgenerational epigenetic effects on thyroid and metabolism in adults
A long-term NIH grant is studying how epigenetic changes passed from parents may influence obesity, thyroid problems, and type 2 diabetes in people.
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MaineHealth Cancer Care Network: cancer care and research for all ages
This program brings cancer prevention, treatment, and clinical trial options closer to children, adolescents, and adults across Maine.
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Beta-1 blockers to reduce heart injury after brain bleed
A patient-focused project aims to use beta-blocker medications to lessen heart damage and inflammation after a non-traumatic brain bleed (subarachnoid hemorrhage).
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Telesimulation program to sustain neonatal resuscitation skills in rural hospitals
A funding opportunity to keep neonatal resuscitation skills sharp in rural Maine hospitals using regular online practice.
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Supporting opioid use disorder care in the ICU with a clinician dashboard and education
Aimed at improving how ICU teams in MaineHealth identify and treat opioid use disorder, using a clinician dashboard, tailored education, and language processing to standardize care.
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Community Engagement, Bioethics, and Outreach Core for rural acute care research
A program to help rural communities participate in time-sensitive medical research by improving ethics, community involvement, and regulatory support.
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Administrative and Professional Development Core for acute care and rural health research
A program to grow and support early-career researchers in acute care and rural health, building robust research infrastructure at MaineHealth.
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Phase 2 Center of Biomedical Research Excellence in Acute Care Research and Rural Health
A rural health research center in Maine is expanding its efforts to improve urgent care outcomes like cardiac arrest and stroke by growing clinician-scientist leadership and collaborating with local partners.
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Neuregulin (ErbB3) signaling in immune cells that protect the heart
This work looks at how a protein called ErbB3 in certain immune cells helps calm inflammation and protect the heart after injury.
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Allelic Dio3 control of brain development and behavior in mood and neurodevelopmental disorders
A research project explores how a gene called Dio3 might shape brain development and behavior, potentially helping people with mood and neurodevelopmental conditions.
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How mitochondria guide bone and fingertip regrowth after injury
This project looks at whether two mitochondrial proteins, BNIP3 and NIX, help guide bone and soft-tissue regrowth after fingertip or limb injuries.
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Immune cell protection after cardiac arrest
This project looks at whether immune cells that produce adenosine can calm inflammation and help people recover after cardiac arrest.
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How beta blocker medicines might protect bone after menopause
This research looks at whether certain beta blocker medicines can help protect bone density in women after menopause.
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Improving well-being and diabetes care for adults with type 2 diabetes
This project helps adults with type 2 diabetes use self-affirmation to reduce stigma and support better wellbeing and diabetes self-care.
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Night shift work and pregnancy-related diabetes risk
Seeing whether working night shifts raises the chance of gestational diabetes and later type 2 diabetes in women who were pregnant.
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How thyroid conditions in parents might affect their children's health across generations
This work explores how environmental factors affecting a parent's thyroid health might influence their children's risk for conditions like obesity and type 2 diabetes.
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Understanding how fat around blood vessels affects heart and metabolic health
This work explores how the fat surrounding our blood vessels influences heart and metabolic conditions, aiming to find new ways to protect against vascular disease.
Quick answers
How many clinical trials run by Mainehealth are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.