Phase II COBRE on Metabolic Networks and Regulation of Fat and Bone Biology
Official title: Phase II COBRE in Mesenchymal and Neural Regulation of Metabolic Networks
Funded at Mainehealth · NIH-11399835 · Data updated 2026-11-12
A Phase II NIH grant supports a center focused on how fat tissue, bone health, and neural inputs regulate metabolic networks, with aims to grow research capacity and help people affected by metabolic diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mainehealth NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | September 1, 2017 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $2,580,000 |
| NIH project number | 5P20GM121301-09 |
| Project ID | NIH-11399835 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals with metabolic syndrome, obesity-related conditions, or bone health issues who may benefit from advances in metabolic regulation.
✕Less likely to help
Some patients whose conditions are not primarily driven by fat/bone metabolic pathways may see limited direct benefit.
What this research studies
This grant continues a program at MaineHealth to study how adipose tissue, bone biology, and neural signals influence metabolism. It funds core facilities, mentoring, and collaboration among researchers to push forward translational science that could benefit patients with metabolic disorders. Researchers will develop and pilot new projects, train junior scientists, and share advanced techniques in physiology, histopathology, and lipidomics to better understand human health. The center already has a track record of supporting NIH-funded projects and enhancing translational potential for metabolic disease care.
Why it matters
Potential benefit: If successful, the work could lead to new insights and therapies for metabolic diseases that involve fat and bone biology.
How similar studies have gone: Phase I COBRE work has already produced several NIH and foundation awards, showing a strong track record for this approach.
Where this research is happening
-
Mainehealth
Portland, United States Active
Researchers
- Principal investigator: Liaw, Lucy — Mainehealth
- Study coordinator: Liaw, Lucy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.