Sponsor or institution

Clinical trials and research at International AIDS Vaccine Initiative

• 3Clinical trials
• 21NIH research projects
• 6Countries

Newest trials

All recruiting trials (3)

• Vaccine study to see if rVSV∆G-SUDV-GP protects adults from Sudan virus disease

  We are testing a vaccine to see if it can safely provoke an immune response to Sudan virus in healthy adults aged 18–50.

  Recruiting at 3 sites Phase 1 International AIDS Vaccine Initiative · Washington D.C., District of Columbia and 2 other locations · NCT07565090

• Gorilla adenovirus (GRAdHIVNE1) vaccine for adults with and without HIV

  This Phase 1 test checks if the GRAdHIVNE1 gorilla adenovirus vaccine is safe and can trigger T-cell immune responses in adults with and without HIV in Southern Africa.

  Recruiting at 3 sites Phase 1 International AIDS Vaccine Initiative · Mtubatuba, KwaZulu-Natal and 2 other locations · NCT06617091

• Lassa Fever Vaccine for Adults and Children in West Africa

  This study is testing a new vaccine for Lassa fever in adults and children in West Africa to see if it's safe and effective at different doses.

  Recruiting at 3 sites Phase 2 International AIDS Vaccine Initiative · Accra and 2 other locations · NCT05868733

NIH-funded research (21)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Creating vaccines for influenza and other infectious diseases

  This study is all about creating new vaccines to help protect people from the flu and other infections, so patients can look forward to better options for staying healthy.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-9952278

• Developing vaccines and biologics for infectious diseases

  This study is working on creating and improving vaccines to help protect people from infectious diseases like the flu and Nipah virus, so that patients can have better options for staying healthy.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-9916844

• Creating vaccines for human trials against influenza and other infectious diseases

  This study is working on creating new vaccines to help protect people from flu and other infectious diseases, including those that could be used in harmful situations, so that everyone can have safer and more effective options to stay healthy.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-9789450

• Developing and producing new vaccines for infectious diseases.

  This study is all about creating and testing new vaccines to help protect people from infectious diseases, including those that could come from bioterrorism or drug-resistant germs, so that patients can have better options for staying healthy.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-9724120

• New mRNA vaccines to prevent tuberculosis for adolescents and adults

  A new mRNA vaccine approach aims to prevent TB in teens and adults and reduce transmission, using advanced vaccine technology.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-11360153

• New mRNA Vaccines for Tuberculosis

  This research explores new mRNA vaccine technology to protect adolescents and adults from tuberculosis, a serious lung infection.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-11325903

• Creating vaccines for influenza clinical trials

  This study is all about creating and testing new flu vaccines to make sure they're safe and effective for people, and it aims to help bring better options to those who need them.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-11127337

• Creating materials for testing new influenza vaccines

  This study is all about creating and improving materials for new flu vaccines, so we can make better vaccines that help keep everyone healthier and prevent the flu.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-11042053

• Optimizing cell lines for a Hepatitis B vaccine

  This study is working on creating a new vaccine to help protect people from Hepatitis B, and it aims to make sure the vaccine is safe and effective for everyone who might need it.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10937202

• Developing new biopharmaceutical products for infectious diseases

  This study is all about helping scientists create new medicines, like antibodies and proteins, to treat infections, so that patients can eventually benefit from these innovative therapies in the future.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10934767

• Developing new treatments to combat bacterial resistance using biopharmaceuticals

  This study is working on new treatments to help fight infections caused by bacteria that are hard to treat, using special tools like antibodies and RNA, and it's designed for anyone interested in better options for managing these tough infections.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10934766

• Developing nanoparticles to deliver HIV-1 vaccines

  This study is working on tiny particles that can help deliver better vaccines for HIV, aiming to create safer and more effective options to help prevent HIV infection for people at risk.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10863796

• Optimizing cell lines for a Hepatitis B vaccine

  This study is working on creating a new vaccine to protect against Hepatitis B, which could help patients by providing a reliable way to prevent this virus in the future.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10787972

• Developing vaccines and biologics for infectious diseases

  This study is working on creating new vaccines to help fight infectious diseases, including those that could come from bioterrorism, so that patients can have better protection and treatment options in the future.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10490543

• Developing vaccines and biologics for infectious diseases

  This study is working on creating new vaccines to help protect people from serious infections, including those that could come from bioterrorism, so that patients can have better options for staying healthy.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10490542

• Optimizing cell lines for a Hepatitis B vaccine

  This study is working on making better cell lines to help create a safer and more effective vaccine for Hepatitis B, so that we can have a new way to fight this virus.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10488144

• Developing new vaccines for infectious diseases

  This study is all about developing and improving new vaccines to help fight infectious diseases, making sure they meet safety standards so they can be approved for use and ultimately help keep everyone healthier.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10390262

• Optimizing cell lines for a Hepatitis B vaccine

  This study is working on making better cell lines to help create a new vaccine for Hepatitis B, so we can fight this virus and related diseases more effectively.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10269959

• Creating vaccines for flu challenge trials

  This study is all about creating and testing new flu vaccines to help make them safer and more effective for people, so we can better protect everyone from getting sick.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10269863

• Developing vaccines for infectious diseases including SARS-CoV-2

  This study is working on creating new vaccines to help protect people from serious infections, especially those that could be used in bioterrorism or are coming back, so that patients can have better options for staying healthy.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10168830

• Creating cell banks for vaccine development to prepare for pandemics

  This study is working on making special cell banks to help create new vaccines that can protect people from infectious diseases, including those that might come from bioterrorism, so that we can respond quickly during health emergencies.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-10168829

Quick answers

How many clinical trials run by International AIDS Vaccine Initiative are recruiting right now?

3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in Ghana (1 trial), Liberia (1 trial), Nigeria (1 trial), South Africa (1 trial), Zimbabwe (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →