NIH-funded research NIH-funded research

Developing nanoparticles to deliver HIV-1 vaccines

Official title: Nanoparticle-based development for HIV-1 biomolecule delivery

Funded at International AIDS Vaccine Initiative · NIH-10863796 · Data updated 2026-11-12

This study is working on tiny particles that can help deliver better vaccines for HIV, aiming to create safer and more effective options to help prevent HIV infection for people at risk.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionInternational AIDS Vaccine Initiative
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 15, 2021
Project endJuly 31, 2026
Funding year2023
Award (this year)$635,012
NIH project number272201600011I-P00003-759302100239-1
Project IDNIH-10863796 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals at high risk for HIV infection or those interested in participating in HIV vaccine trials.

Less likely to help

Patients who are already living with HIV or those who are not at risk for HIV infection may not benefit from this research.

What this research studies

This research focuses on creating nanoparticles that can effectively deliver biomolecules for HIV-1 vaccine development. By utilizing advanced techniques in chemistry and molecular biology, the project aims to enhance the delivery and efficacy of potential vaccines against HIV. The approach includes process development and analytical characterization to ensure that the vaccines can progress through clinical trials safely and effectively. Patients may benefit from improved vaccine options that could lead to better prevention of HIV infection.

Why it matters

Potential benefit: If successful, this research could lead to more effective vaccines that significantly reduce the risk of HIV infection.

How similar studies have gone: Other research has shown promise in using nanoparticle delivery systems for vaccines, indicating a potential for success in this novel approach.

Where this research is happening

  • International AIDS Vaccine Initiative
    New York, United States
    Active

Researchers

  • Principal investigator: Hassell, Thomas — International AIDS Vaccine Initiative
  • Study coordinator: Hassell, Thomas

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.