Optimizing cell lines for a Hepatitis B vaccine
Task V24: Cell line optimization and pre-master bank generation for a Hepatitis B Virus (HBV) vaccine
['FUNDING_OTHER'] · INTERNATIONAL AIDS VACCINE INITIATIVE · NIH-10488144
This study is working on making better cell lines to help create a safer and more effective vaccine for Hepatitis B, so that we can have a new way to fight this virus.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INTERNATIONAL AIDS VACCINE INITIATIVE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10488144 on ClinicalTrials.gov |
What this research studies
This research focuses on improving cell lines used in the production of a vaccine for Hepatitis B Virus (HBV). It involves developing and optimizing these cell lines to ensure they meet the necessary standards for safety and efficacy. The project includes planning, feasibility assessments, and compliance with regulatory requirements for clinical trials. By enhancing the manufacturing process, the research aims to facilitate the introduction of a new vaccine that can effectively combat HBV.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk of Hepatitis B infection, including those with chronic liver disease or those in high-risk populations.
Not a fit: Patients who are already vaccinated against Hepatitis B or those with no risk factors for the virus may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of a more effective vaccine against Hepatitis B, potentially reducing the incidence of this infectious disease.
How similar studies have performed: Other research in vaccine development has shown success with similar optimization approaches, indicating a promising pathway for this project.
Where this research is happening
NEW YORK, UNITED STATES
- INTERNATIONAL AIDS VACCINE INITIATIVE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HASSEL, THOMAS — INTERNATIONAL AIDS VACCINE INITIATIVE
- Study coordinator: HASSEL, THOMAS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Infectious Disease Pathway, Infectious Diseases, Infectious Disorder, Communicable Diseases