Creating vaccines for influenza clinical trials
Official title: Task V02: Manufacture of Influenza for Human Challenge Clinical Trials
Funded at International AIDS Vaccine Initiative · NIH-11127337 · Data updated 2026-11-12
This study is all about creating and testing new flu vaccines to make sure they're safe and effective for people, and it aims to help bring better options to those who need them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | International AIDS Vaccine Initiative NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 15, 2018 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $136,951 |
| NIH project number | 272201800010I-P00005-27200002-1 |
| Project ID | NIH-11127337 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation would include healthy adults who are willing to receive an influenza vaccine as part of a clinical trial.
✕Less likely to help
Patients with severe allergies to vaccine components or those with compromised immune systems may not benefit from this research.
What this research studies
This research focuses on the manufacturing and characterization of influenza vaccines for human challenge clinical trials. It involves developing and optimizing vaccine products, ensuring compliance with regulatory standards, and preparing them for clinical testing. The approach includes comprehensive planning, technical audits, and support for FDA submissions, aimed at facilitating the introduction of new vaccines and biologics to combat influenza. Patients may be involved in trials that assess the safety and efficacy of these vaccines.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective influenza vaccines, improving prevention and treatment options for patients.
How similar studies have gone: Previous research has shown success in developing vaccines through similar manufacturing and clinical trial approaches.
Where this research is happening
-
International AIDS Vaccine Initiative
New York, United States Active
Researchers
- Principal investigator: Hassel, Thomas — International AIDS Vaccine Initiative
- Study coordinator: Hassel, Thomas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.