Creating vaccines for flu challenge trials
Official title: Task V02: Manufacture of Influenza for Human Challenge Clinical Trials
Funded at International AIDS Vaccine Initiative · NIH-10269863 · Data updated 2026-11-12
This study is all about creating and testing new flu vaccines to help make them safer and more effective for people, so we can better protect everyone from getting sick.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | International AIDS Vaccine Initiative NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 15, 2018 |
| Project end | May 14, 2028 |
| Funding year | 2020 |
| Award (this year) | $96,744 |
| NIH project number | 272201800010I-P00003-27200002-1 |
| Project ID | NIH-10269863 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation would include individuals who are at risk for influenza or those interested in contributing to vaccine development.
✕Less likely to help
Patients who are not at risk for influenza or those who have contraindications to vaccination may not benefit from this research.
What this research studies
This research focuses on the manufacturing and characterization of vaccines specifically for clinical trials involving influenza. It involves developing and optimizing vaccine candidates, ensuring compliance with regulatory standards, and preparing materials for human challenge studies. Patients may benefit from this research as it aims to enhance the development of effective vaccines against influenza, potentially leading to better prevention strategies. The approach includes rigorous product development planning and technical audits to ensure safety and efficacy.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective vaccines against influenza, improving public health outcomes.
How similar studies have gone: Previous research has shown success in developing vaccines through similar manufacturing and characterization approaches, indicating a promising pathway for this project.
Where this research is happening
-
International AIDS Vaccine Initiative
New York, United States Active
Researchers
- Principal investigator: Hassell, Thomas — International AIDS Vaccine Initiative
- Study coordinator: Hassell, Thomas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.