Sponsor or institution
Clinical trials and research at Clemson University
As of November 12, 2026, Find a Trial lists 2 clinical trials run by Clemson University that are recruiting, in United States. There are also 139 NIH-funded research projects at this institution, with $61.9 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 2Clinical trials
- 139NIH research projects
- 1Country
All recruiting trials (2)
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Fueling Strong Hearts for South Carolina stroke survivors.
This program will test whether a virtual lifestyle program that adds medically tailored groceries to a peer-led exercise and nutrition class helps adults 45–80 with chronic stroke and overweight or obesity improve activity, diet, and quality of life.
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Peer recovery coaching for hospitalized patients with alcohol use disorder
This study is testing whether a peer recovery coaching program can help hospitalized patients with alcohol use disorder drink less and improve their overall well-being.
NIH-funded research (newest 40 of 139)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Tissue Structure and Nerve Changes in the Sacroiliac Joint
Researchers are studying how the sacroiliac joint contributes to low back pain by looking at its tissue structure and nerve-related changes.
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Regulation of Cryptosporidium Development in Kids and Communities
Scientists are studying how Cryptosporidium, a parasite that causes severe diarrhea from dirty water, develops, with the goal of finding new treatments for people who get sick.
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ATTRACT: How jaw shape and movement affect jaw joint health in adults with jaw misalignment
This project studies how the shape and movement of the jawbone in adults with Class II or III jaw misalignment relate to the health and mechanics of the jaw joint.
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Noninvasive nanoparticle therapy for the peripheral nervous system
Aimed at improving delivery of non-invasive treatments to injured nerves, this grant funds equipment to study how nanoparticles can cross the blood-nerve barrier and support nerve repair.
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Health Extension for Diabetes: Connecting Community and Clinic
A community-clinical program aims to improve diabetes care by linking local health resources with clinical services over a two-year period.
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Ice-free Preservation and Nanowarming for Viable Meniscal Transplants
Aimed at helping people with serious knee meniscus damage by improving how donor meniscal tissue is preserved so it stays alive longer.
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How Smoking Affects the Rotator Cuff Tendon-Bone Attachment
This project studies how cigarette smoking changes the healing and strength of the tendon–bone connection in the shoulder after injury, using a smoking chamber and rat models.
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Preclinical Assessment Core supports musculoskeletal research and translation
A dedicated center helps scientists study bone and joint disorders using animal and human cadaver models to improve patient care.
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Advanced Fabrication and Testing Core supports patient-focused musculoskeletal research
A specialized engineering core at Clemson helps translation-ready musculoskeletal research by providing rapid fabrication, testing, and customization for projects aiming to improve diagnosis and treatment at the molecular, cellular, tissue, and whole-body levels.
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Multi-Scale Computational Modeling Core with AI for Bioengineering and Musculoskeletal Health
A research core at Clemson University is using advanced computer models and AI to simulate how interventions and devices affect the human body, with a focus on musculoskeletal health.
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Administrative Core for SC-TRIMH: Strengthening Musculoskeletal Health Translational Research
A centralized administrative core supports a translational musculoskeletal health center to help move findings from the lab toward patient care.
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Translational Musculoskeletal Health with Virtual Human Trials at Clemson
A Clemson-based program expands musculoskeletal research by using Virtual Human Trials to speed up development of devices, therapies, and interventions that could help adults with musculoskeletal illnesses.
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A Peer Recovery Coaching Program for Hospitalized Patients with Alcohol Use Disorder
A hospital-based program connects patients with alcohol use disorder to peer recovery coaches to support ongoing care after discharge.
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Cell State Network–Directed Therapy for Cancer
A cancer research project that aims to outsmart drug resistance by using a network view of cancer cell states to guide combination therapies.
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Understanding how genes interact with context to shape complex traits
This NIH grant looks at how our genes work together with other factors to influence common diseases and traits, with the goal of improving risk predictions for people.
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Septin proteins and how the fungus Cryptococcus adapts to human body temperature
Researchers explore how the fungus Cryptococcus neoformans changes at body temperature, which may help prevent deadly infections in people with HIV/AIDS.
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Data-driven opioid use disorder care in rural areas using mobile clinics and peer support
A rural-focused program will test how data-driven tools, mobile clinics, and peer support can help people start and stay on opioid use disorder treatment and prevent overdoses.
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Blocking IAPP protein clumps to protect insulin-producing cells
Aims to stop the clumping of a protein (IAPP) that harms insulin-making cells in type 2 diabetes, with potential ripple effects for related brain diseases.
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Novel split-enzyme diagnostic platform for rapid, at-home biomarker detection
A new, ultra-sensitive diagnostic approach uses split enzyme signals to detect biomarkers quickly at the point of care, potentially enabling affordable, bedside testing.
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Advanced metabolomics tools to study deadly brain infection organisms
Researchers will use high-resolution ion mobility and tandem mass spectrometry to better understand the metabolites involved in infections caused by brain-threatening pathogens like Naegleria fowleri and Aspergillus fumigatus, with potential to improve diagnosis and treatments.
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Understanding how malaria parasite feeds and invades red blood cells
Researchers are studying how Plasmodium falciparum reshapes human red blood cells to survive, which could lead to better strategies against malaria.
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Understanding a fungal RNA that drives drug tolerance to improve Aspergillus infections
Researchers are studying a specific RNA in the fungus Aspergillus fumigatus to understand why some infections resist common antifungal drugs, with the goal of guiding better treatments for patients with immune-compromised conditions.
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Clemson Imaging and Cell Sorting Core for COBRE (CLIF)
A shared imaging and cell-sorting resource at Clemson University supports cancer biology and other life-science research by providing advanced microscopy and cytometry capabilities for multiple researchers.
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Clemson’s genomics and bioinformatics facility to boost research training and capacity
A center at Clemson helps junior researchers in biology and bioinformatics gain access to advanced gene analysis tools and training to build stronger preliminary data for future NIH funding.
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Administrative Core for EPIC: Advancing Eukaryotic Pathogens Research at Clemson
A center grant supporting Clemson University’s Eukaryotic Pathogens Innovation Center to grow expertise, mentor researchers, and coordinate research on disease-causing eukaryotic pathogens.
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EPIC: A Center to study human-infecting eukaryotic pathogens
A center at Clemson will research harmful eukaryotic pathogens like fungi and parasites to improve understanding and treatment for diseases such as malaria, sleeping sickness, amebic dysentery, and more.
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How gut bacteria build and balance our microbiome
A study looking at how the trillions of bacteria in the gut come together and function from birth to later life, to understand how a healthy gut supports overall health.
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High-speed imaging tools to study protein interactions in cancer cells
Researchers are developing advanced imaging methods to watch how proteins interact in cancer cells in real time, aiming for ultra-precise detail.
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Nonviral CRISPR-Cas9 delivery to liver cells to treat familial hypercholesterolemia
A new approach uses nonviral methods to deliver CRISPR-Cas9 to liver cells and select edited cells with acetaminophen, aiming to permanently lower bad cholesterol in people with familial hypercholesterolemia.
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Improving opioid treatment and overdose prevention in rural areas with mobile clinics and peer support
This project uses mobile health clinics and trained peer support specialists to help people with opioid use disorder in rural communities start and stay on medication and avoid overdoses.
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New chemical methods to make rare nitrogen-rich rings and tool compounds to study gut bacteria
Researchers at Clemson are developing new chemistry to create rare nitrogen-rich molecules and special tool compounds to better understand how gut bacteria metabolize polysaccharides, with potential implications for autoimmune diseases and infections.
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Nanowired hypoimmunogenic heart organoids for repairing damaged hearts
A study tests specially designed stem-cell–derived heart tissue that is engineered to be less likely to cause immune rejection when implanted to repair hearts after a heart attack.
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How ACE‑inhibitor drugs may work with genes to support longer, healthier lives
This work looks at whether the blood‑pressure drug lisinopril acts through specific genes to help preserve movement and cellular energy as organisms age, with the goal of learning how to keep people healthier longer.
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Genes that affect how people respond to cocaine
Using fruit flies to find genes that may change how people react to cocaine and to inform future treatments for addiction.
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Nanowired lab-grown human heart tissue particles to help hearts heal after a heart attack
Developing tiny particles made by lab-grown human heart tissues to help people recover after an acute heart attack.
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Targeted treatment to repair and strengthen aortic aneurysms
A nanoparticle therapy that homes to damaged aortic tissue and delivers a natural compound to rebuild and stabilize the artery wall is being developed for people with abdominal aortic aneurysms to try to stop growth and rupture.
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Safety of tin‑silver metal used in implants
This project is checking whether the tin‑silver metal used in some implants like Essure breaks down in the body and could harm people who have those devices.
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Smartwatch tracking of eating and calories
This project uses a smartwatch to passively count bites and sips and estimate calories for adults with or at risk for type 2 diabetes.
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Nanowire-enhanced human heart organoids to repair damaged hearts
Researchers are developing tiny silicon-wire–boosted lab-grown human heart tissue to help people recover heart function after a heart attack.
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How jaw shape affects TMJ health in adults with Class II or Class III bite differences
This project looks at how differences in jaw shape change joint forces and tissue biology in adults with Class II or Class III bite differences to help explain TMJ pain and degeneration.
Quick answers
How many clinical trials run by Clemson University are recruiting right now?
2, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.