Translational Musculoskeletal Health with Virtual Human Trials at Clemson
Official title: SC COBRE for TranslationalResearch Improving MusculoskeletalHealth (SC-TRIMH)
Funded at Clemson University · NIH-11413681 · Data updated 2026-11-12
A Clemson-based program expands musculoskeletal research by using Virtual Human Trials to speed up development of devices, therapies, and interventions that could help adults with musculoskeletal illnesses.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Clemson University NIH-funded |
| Lab location | 1 site (Clemson, United States) |
| Project start | September 15, 2018 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $2,209,168 |
| NIH project number | 5P20GM121342-09 |
| Project ID | NIH-11413681 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with musculoskeletal conditions who may benefit from new devices, therapies, or interventions developed through Virtual Human Trials.
✕Less likely to help
Some patients may not directly benefit if a specific device or therapy is not effective for their condition.
What this research studies
This grant supports a translational science hub at Clemson University that uses computational models and real-world validation to move promising musculoskeletal therapies toward patient care. It builds on Phase I by expanding the Virtual Human Trials paradigm, strengthening research cores, and supporting junior investigators to pursue patient-centered projects. The effort aims to shorten the path from discovery to real benefits for adults with musculoskeletal conditions. Researchers will collaborate across disciplines to develop and test new devices, interventions, and therapeutics in a patient-relevant framework.
Why it matters
Potential benefit: If successful, patients could receive faster access to effective new treatments and devices for musculoskeletal health.
How similar studies have gone: Previous phases showed that Virtual Human Trials can accelerate translational work and inform safer, more effective interventions.
Where this research is happening
-
Clemson University
Clemson, United States Active
Researchers
- Principal investigator: Yao, Hai — Clemson University
- Study coordinator: Yao, Hai
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.