NIH-funded research NIH-funded research

Multi-Scale Computational Modeling Core with AI for Bioengineering and Musculoskeletal Health

Official title: Multi-Scale Computational Modeling Core (MCM)

Funded at Clemson University · NIH-11413711 · Data updated 2026-11-12

A research core at Clemson University is using advanced computer models and AI to simulate how interventions and devices affect the human body, with a focus on musculoskeletal health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionClemson University
NIH-funded
Lab location1 site (Clemson, United States)
Project startSeptember 15, 2018
Project endJuly 31, 2028
Funding year2026
Award (this year)$306,124
NIH project number5P20GM121342-09
Project IDNIH-11413711 on NIH RePORTER

Who could benefit from this research

Could help

Patients with musculoskeletal health concerns who may participate in or be impacted by computational virtual trials or future device/therapy testing.

Less likely to help

This core is infrastructure-focused and does not involve direct patient recruitment or a clinical trial itself.

What this research studies

This grant funds a core that develops and runs multi-scale computer models—from molecules to populations—to predict how new therapies and devices will affect people. It adds AI and machine learning to handle big data and improve prediction accuracy for virtual human trials. The core also provides guidance, training, and computation resources to SC-TRIMH investigators to maximize modeling impact. Researchers collaborate across disciplines to translate computational insights into safer and more effective interventions for body health. The work aims to become a regional hub for AI-enabled computational bioengineering in South Carolina.

Why it matters

Potential benefit: If successful, patients could benefit from faster, more accurate predictions of how new treatments or devices may affect them before clinical testing.

How similar studies have gone: Similar AI-augmented multi-scale modeling efforts have shown promise in improving the design and evaluation of biomedical interventions.

Where this research is happening

  • Clemson University
    Clemson, United States
    Active

Researchers

  • Principal investigator: Yao, Hai — Clemson University
  • Study coordinator: Yao, Hai

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.