Noninvasive nanoparticle therapy for the peripheral nervous system
Official title: Noninvasive nanoparticle-directed therapy to the peripheral nervous system
Funded at Clemson University · NIH-11550114 · Data updated 2026-11-12
Aimed at improving delivery of non-invasive treatments to injured nerves, this grant funds equipment to study how nanoparticles can cross the blood-nerve barrier and support nerve repair.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Clemson University NIH-funded |
| Lab location | 1 site (Clemson, United States) |
| Project start | July 4, 2025 |
| Project end | March 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $26,459 |
| NIH project number | 3R01NS142877-02S1 |
| Project ID | NIH-11550114 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals with acute or chronic peripheral nerve injuries or diseases affecting dorsal root ganglia and nerve repair processes.
✕Less likely to help
Patients without peripheral nerve injuries likely would not directly benefit from this basic mechanistic work.
What this research studies
This project focuses on understanding how to deliver treatments to damaged nerves without surgery. It will provide equipment to rapidly isolate and culture injured dorsal root ganglia and blood-nerve barrier cells, improving the quality of laboratory models. By enabling closer, faster analysis of nanoparticle delivery in these cells, researchers hope to uncover mechanisms that could lead to better non-invasive therapies for nerve injuries.
Why it matters
Potential benefit: If successful, it could accelerate the development of non-invasive treatments that improve nerve healing and reduce chronic pain.
How similar studies have gone: Prior work shows that understanding the blood-nerve barrier can improve drug delivery to nerves; this study builds on those methods with improved tissue culture and analysis.
Where this research is happening
-
Clemson University
Clemson, United States Active
Researchers
- Principal investigator: Larsen, Jessica — Clemson University
- Study coordinator: Larsen, Jessica
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.