Understanding AMH Levels in Healthy Girls

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to investigate the normal blood levels of anti-mullerian hormone (AMH) in females aged 0-18 years and how these levels relate to their reproductive development. By collecting blood samples from pre- and post-pubertal females undergoing routine outpatient surgical procedures, researchers hope to establish a baseline for AMH levels in this population. This understanding could help assess the risk of infertility in young cancer patients and provide options for preserving fertility. The study focuses on a specific age group and aims to fill the knowledge gap regarding AMH levels in children and adolescents.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Pre- and post-pubertal females
2. Ages 0-18 years old
3. Tanner Stage I- V
4. Undergoing routine outpatient surgical procedure

   1. Hernia repair (inguinal, umbilical, epigastric)
   2. Excision of benign mass
   3. laparoscopic cholecystectomy

Exclusion Criteria:

1. Previous diagnosis of an illness associated with premature ovarian failure (Turner's syndrome, Fragile X permutation carrier) or endocrine disorder associated with irregular menstrual cycles (Cushing's disease, poorly-controlled Thyroid disease, hyperprolactinemia, polycystic ovary syndrome, and congenital adrenal hyperplasia) or insulin-dependent diabetes mellitus or autoimmune disorders
2. Previous diagnosis of any malignancy or any history of systemic/local chemotherapy, radiation therapy, or stem-cell transplant.
3. Previous surgical excision of one ovary or both ovaries
4. Pregnant females
5. All inpatient surgical patients
6. Undergoing non-routine outpatient surgical procedures

   1. Central venous catheter placement
   2. Supprelin insertion/removal
   3. Breast mass excision
   4. Gastrostomy tube insertion

Where it's running

• Ann & Robert H Lurie Children's Hospital of Chicago
  Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: Erin Rowell, MD — Ann & Robert H Lurie Children's Hospital of Chicago
• Study coordinator: Jacquelyn Searcy
• Email: FertilityPreservationMB@luriechildrens.org
• Phone: 3122274758

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.